A Comprehensive Review On Synthetic Routes and Pharmacological Activities of Pyrazoles and Quinolines

ABSTRACT

In the modern world, a number of heterocycles have emerged and are showing important roles in a variety of human-beneficial pharmaceutical compounds. Pyrazoles are nitrogen-containing heterocyclic compounds with five members. They have garnered a lot of attention because they belong to a significant class of chemicals for therapeutic development and Quinolines, A typical example of bicyclic heterocyclic compounds. Meanwhile, derivatives of pyrazole and quinoline have been synthesized as target structures and have shown a wide range of biological actions, including antitubercular, anticancer, antifungal, anti-inflammatory, antibacterial, and anti-tuberculosis properties. The findings of published studies on the synthesis and biological activity of quinoline and pyrazole derivatives are compiled in this review. The Scopus database was consulted to gather and evaluate the published research papers on the biological activities and synthesis of pyrazole and quinoline derivatives that were published between January 2019 and December 2023.

Keywords: Heterocycles, pyrazoles, quinoline, anticancer, anti-inflammatory, research papers.