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Published July 28, 2025 | Version 2025.07.28
Dataset Open

Diamond2GO Database – Version 2025-07-28 (nr_clean_d2go)

  • 1. ROR icon University of Exeter

Description

This is the updated Diamond2GO reference database built on 28th July 2025.

It is a DIAMOND-formatted protein database (`.dmnd`) consisting of over 34 million sequences derived from the NCBI `nr` dataset, filtered to include only those with Gene Ontology (GO) annotations. This version significantly improves sensitivity and annotation coverage compared to the original 2023 release used in the published D2GO manuscript.

This database is intended for use with the Diamond2GO tool, which enables rapid GO-term annotation and enrichment analysis for high-throughput sequencing datasets.

For reproducibility of results published using the earlier version (699,409 sequences), please refer to the [v1.0.0 release] https://github.com/rhysf/Diamond2GO/releases/tag/6a035ce

Files

Files (32.0 GB)

Name Size Download all
md5:c8c82a76c0b9a530ec432b259659d7b6
66 Bytes Download
md5:dae60f74a690a31fc111c10b6c2c38fd
4.2 GB Download
md5:be38bbbd7fd01fcdf3443d8483ece285
74 Bytes Download
md5:9b63c8319f11c4ceb1c2090c61ef9ecb
4.2 GB Download
md5:02838a9f49aac2edb685340ddb9a4da3
74 Bytes Download
md5:2e3146554052b9b5c1a0fbcbaf637179
4.2 GB Download
md5:0213ea4594c38b68b6df289e5fc3b255
74 Bytes Download
md5:67468047cdb9609c0d7e8d21e22d7c98
4.2 GB Download
md5:d6b6c4ac32a8be88a27662f402d27096
74 Bytes Download
md5:a76fe0a2a805f90ffd8d2fca79d2aedd
4.2 GB Download
md5:5303a48524fa24afc02cc99ea72b8f0b
74 Bytes Download
md5:7f3da82dd9ad481ec8647107d9c209c9
4.2 GB Download
md5:4da1fc70ddee0352b7dc9796f23a8343
74 Bytes Download
md5:211b9b9019839bdccee7e389754a0613
4.2 GB Download
md5:41a0d077fff3e72e8bbdec4a6171feb7
74 Bytes Download
md5:301ac06543f379cbdc9bef691ab2c948
2.7 GB Download
md5:2e52d35983bb3a22b3fab133260ce984
74 Bytes Download

Additional details

Related works

Is documented by
Dataset: https://github.com/rhysf/Diamond2GO (URL)
Is supplement to
Dataset: 10.3389/fbinf.2025.1634042 (DOI)

Funding

Wellcome Trust
Mechanistic insights into fungal pathogenicity and drug resistance using a novel lineage of Cryptococcus 225303

Dates

Available
2025-07-28

Software

Repository URL
https://github.com/rhysf/Diamond2GO
Development Status
Active