Published October 1, 2013 | Version v1
Book chapter Restricted

MRI - with applications in neurological disorders

  • 1. Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium
  • 2. Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium and Experimental Cell Transplantation Group, Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium

Description

MRI has developed into one of the most powerful

techniques for both experimental and clinical research.

 Nowadays, it has become the imaging method of choice

for modern medical imaging and its success is due to its

 versatile nature. In addition, it is noninvasive and offers the

advantage of imaging at relatively high spatial as well as

high temporal resolution. The main advantage of MRI

compared with other common imaging techniques such as

 positron emission tomography and single-photon emission

computed tomography is its very high in vivo spatial

 resolution resulting in clear anatomical information. In

addition, it provides an amazingly strong imaging contrast

between different soft tissues, which is not feasible with

other in vivo  imaging modalities. Since magnetic fields and

low-energy electro-magnetic waves are used instead of

ionizing radiation, no biological damage is caused. Another

important advantage is that MRI allows longitudinal

studies, since it does not rely on the use of radioactive

isotopes. This chapter highlights the most commonly used

 MRI techniques in both clinical and preclinical practice.

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Additional details

Funding

European Commission
INMIND – Imaging of Neuroinflammation in Neurodegenerative Diseases 278850