MRI - with applications in neurological disorders
- 1. Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium
- 2. Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium and Experimental Cell Transplantation Group, Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium
Description
MRI has developed into one of the most powerful
techniques for both experimental and clinical research.
Nowadays, it has become the imaging method of choice
for modern medical imaging and its success is due to its
versatile nature. In addition, it is noninvasive and offers the
advantage of imaging at relatively high spatial as well as
high temporal resolution. The main advantage of MRI
compared with other common imaging techniques such as
positron emission tomography and single-photon emission
computed tomography is its very high in vivo spatial
resolution resulting in clear anatomical information. In
addition, it provides an amazingly strong imaging contrast
between different soft tissues, which is not feasible with
other in vivo imaging modalities. Since magnetic fields and
low-energy electro-magnetic waves are used instead of
ionizing radiation, no biological damage is caused. Another
important advantage is that MRI allows longitudinal
studies, since it does not rely on the use of radioactive
isotopes. This chapter highlights the most commonly used
MRI techniques in both clinical and preclinical practice.