A REVIEW ON OPTIMIZATION OF GROWTH PARAMETERS FOR ENHANCED FUNGAL LIPASE PRODUCTION

Lipases catalyze hydrolysis of fat/lipid into their components. Microbial lipases are preferred than the animal and plant lipases because of their stability, specificity and unique properties. Microbial lipases are excreted by a variety of bacteria, fungi and yeasts. Lipases are used in various industries (pharmaceutical, food, detergent, oil, paper etc). At present the demand of industries for lipases are very higher, therefore we have to increase the production of enzyme form indigenous microbial strains in order to fulfill the various applications in industries. Normally microbial strain produces little amount of lipases to meet the cellular requirements but for the industrial purposes, the amount of lipases can be enhanced by the optimization technique. Different parameters (carbon sources, nitrogen sources, pH, temperature and incubation period) can be optimized in order to increase productivity of lipase. Lipase production is normally stimulated in presence of lipidic carbon sources (oil) into the culture media, which indicates the inducible nature of microbial lipases. By keeping the above points in mind, the present review is focused on optimization of culture medium constituents and growth conditions for increased growth of lipolytic fungi and productivity of extracellular lipase. Keywords: Lipases, microbial strains, optimization technique, lipolytic fungi, pH, temperature, carbon source