GWAS summary statistics for self-reported high cholesterol (UK Biobank Data-Field 20002; Coding 1473)

GWAS summary statistics for self-reported high cholesterol in the UK Biobank (Data-Field 20002; Coding 1473), output by PLINK2 software. 

This includes:

• P-values for each SNP (three rows per SNP, ordered by additive test TEST = "ADD"; dominance test TEST = "DOMDEV" and the 2-df joint test TEST = "GENO_2DF"), obtained from the genotypic model where both additive and dominance effects are included
  (file: bri_result_high_chol.self_reported_cholesterol.glm.logistic.hybrid). and

• P-values for each SNP from the traditional additive test, where the model is additive-only
  (file: bri_result_high_chol_additive.self_reported_cholesterol.glm.logistic.hybrid).

Please note that for the traditional additive GWAS result, one should refer to the second file, not to the first file (where TEST = "ADD").

Each variable (column) in the PLINK2 summary is interpreted as the following:

• #CHROM: The chromosome number.
• POS: GRCh37 position.
  
• ID: The SNP ID.
• REF: Reference Allele.
• ALT: Alternate Allele.
• A1: The Effect Allele.
• FIRTH?: Whether to use the Firth implementation for the logistic regression.
• TEST: Indication of the type of hypothesis test to perform ("GENO_2DF": joint test; "DOMDEV": dominance test; "ADD": additive test)
• OBS_CT: Number of samples included in the analysis.
• OR: Odds ratio.
• LOG(OR)_SE: Standard error of the log odds ratio.
  
• (first file) Z_OR_F_STAT: Wald Statistics for the 1-df test (TEST = "DOMDEV" or "ADD") and the 2-df test (TEST = "GENO_2DF").
• (second file) Z_STAT: Z Statistics for the test.
• P: P-value for the test.
• ERRCODE: Error code ("." means no error).