"The role of nursing in the early detection of sepsis in critically ill patients: a multi-centre study."

Abstract: Sepsis is a life-threatening condition characterized by organ dysfunction due to a dysregulated host response to infection. It continues to be a leading cause of mortality among critically ill patients, particularly in intensive care units (ICUs). The early detection of sepsis is crucial for improving survival rates and minimizing complications. Nurses, who provide continuous care at the patient’s bedside, play a pivotal role in the early identification of sepsis symptoms. This review synthesizes evidence from multi-center studies and explores the role of nurses in recognizing early warning signs, implementing sepsis screening tools, and promoting timely interventions. It highlights the impact of nurse-led protocols, ongoing training, and interdisciplinary collaboration in reducing morbidity and mortality associated with sepsis. Despite significant advancements, challenges such as staffing issues, lack of confidence in clinical judgment, and protocol variations persist. By empowering nurses through training and authority, and integrating technological tools into clinical practice, healthcare systems can enhance sepsis outcomes. This article concludes with recommendations for policy changes and standardized practices to strengthen nursing-led sepsis surveillance across ICU settings.