Re-analysis of human and mouse stromal lung cells
Description
Seurat objects used in "Stromal heterogeneity in the adult lung delineated by single-cell genomics". https://doi.org/10.1152/ajpcell.00285.2025
mNormBleoreannotated.rds : re-annotated Seurat object for mouse stromal cells
hNormIPFreannotated.rds : re-annotated Seurat object for human stromal cells
hLung0827.rds : original Seurat object used to generate hNormIPFreannotated.rds
Update, July 1st, 2025
In the process of generating "hNormIPFreannotated.rds", the cells were accidentally downsampled to half. "hNormIPFreannotated.rds" should still work for annotation transfer. If you need an object without downsampling, you can use "hLung0827.rds", and in "Codes for human object.R",
replace this code
IPF2 <- subset(x = IPF, subset = disease == c("IPF", "Normal"))
with
IPF2 <- subset(x = IPF, subset = disease %in% c("IPF", "Normal"))