Published May 3, 2025 | Version v1
Dataset Open

Re-analysis of human and mouse stromal lung cells

  • 1. ROR icon University of California, San Francisco

Description

Seurat objects used in "Stromal heterogeneity in the adult lung delineated by single-cell genomics". https://doi.org/10.1152/ajpcell.00285.2025

mNormBleoreannotated.rds : re-annotated Seurat object for mouse stromal cells

hNormIPFreannotated.rds : re-annotated Seurat object for human stromal cells

hLung0827.rds : original Seurat object used to generate hNormIPFreannotated.rds

 

Update, July 1st, 2025

In the process of generating "hNormIPFreannotated.rds", the cells were accidentally downsampled to half. "hNormIPFreannotated.rds" should still work for annotation transfer. If you need an object without downsampling, you can use "hLung0827.rds", and in "Codes for human object.R", 

replace this code

IPF2 <- subset(x = IPF, subset = disease == c("IPF", "Normal"))

with

IPF2 <- subset(x = IPF, subset = disease %in% c("IPF", "Normal"))

 

Files

Files (2.0 GB)

Name Size Download all
md5:691eb7c7deddbd982fecfbd1b517737a
5.4 kB Download
md5:691d02bbf75749adc29f22504a074081
4.9 kB Download
md5:280c443fa9eb9e8e656bb4816580d610
292.6 MB Download
md5:55c403baf0f73ecf8645c5e01b23469e
103.0 MB Download
md5:a212226030b5e41c275a0eaa40a0604b
1.6 GB Download

Additional details

Software

Programming language
R