Published April 10, 2025
| Version v0.0.1
Dataset
Open
Caribbean LD files for GhostKnockoffGWAS
Description
This contains pre-processed LD files (Sigma matrix, S matrix, ...etc) computed on Caribbean samples of the UK-Biobank (n = 4517). It is intended to be used as an input to the GhostKnockoffGWAS pipeline.
- This is the output of applying solveblock executable directly on 4517 Caribbean samples of the UK-Biobank.
- Quasi-independent blocks are computed by applying the snp_ldsplit function with parameters thr_r2=0.01, max_r2=0.3, min_size = 500, and max_size = {1000, 1500, 3000, 6000, 10000}.
- SNPs with minor allele frequency less than 0.01 or Hardy-Weinburg equilibrium p-value less than 1e-6 are removed.
- Only HG19 coordinates are available.
- Knockoff optimization were carried out by the Knockoffs.jl julia package: https://github.com/biona001/Knockoffs.jl
- The result (i.e. files available in this site) is saved in .csv and .h5 formatted files for easier access, which is directly readable by GhostKnockoffGWAS.
Files
CRB.zip
Files
(10.4 GB)
Name | Size | Download all |
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md5:5183ee2d98d4c2adcb992541b2e3f423
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10.4 GB | Preview Download |
Additional details
Dates
- Available
-
2025-04-10
Software
- Repository URL
- https://github.com/biona001/GhostKnockoffGWAS