Applications of 9-Chloroacridine in Pharmaceuticals

9-Chloroacridine, a halogenated acridine derivative, has gained significant attention in pharmaceutical research due to its diverse biological activities. This compound serves as a key intermediate in the synthesis of various acridine-based drugs, particularly those with antibacterial, antimalarial, anticancer, and antiviral properties. Its structural framework contributes to DNA intercalation and enzyme inhibition, making it a valuable candidate in chemotherapeutic drug development. Additionally, 9-chloroacridine has been explored for its potential in treating neurodegenerative diseases and as a fluorescent probe in biomedical imaging. Current research focuses on optimizing its pharmacokinetic properties and minimizing toxicity to enhance its therapeutic applications. This review highlights the major pharmaceutical uses of 9-chloroacridine, emphasizing its role in modern drug discovery and development.