Portable In-situ Electrospinning Devices for Personalized Healing in Emergency Wound Care

Portable in-situ electrospinning devices have emerged as a transformative solution for personalized 
wound care, particularly in emergency situations. These devices enable the direct deposition of nanofiber 
layers onto wound sites, providing a protective barrier, promoting hemostasis, and facilitating the 
incorporation of antimicrobial agents and healing accelerators. This review examines the technological 
advancements in portable electrospinning devices, various application methods, and their clinical 
relevance in emergency wound care. The fundamentals of electrospinning technologies, including 
needle-based, needle-free, melt, emulsion, and solution electrospinning, are discussed, elucidating their 
unique strengths and limitations. The development of battery-operated and generator-powered portable 
devices has expanded the scope of electrospinning applications, enabling their utilization in diverse 
environments such as remote locations, surgical settings, and home care. Comparative analysis of 
portable electrospinning devices and traditional methods for wound healing applications reveals the 
potential of these devices to produce nanofiber dressings with enhanced mechanical properties, barrier 
functions, and biocompatibility. However, challenges persist in achieving consistent fiber quality, 
scalability, and further refinement of device portability. The future of portable in-situ electrospinning 
devices presents significant potential for revolutionizing wound care, tissue engineering, and 
personalized medicine, with advancements in automation, material innovation, and the integration of 
bioactive components expected to drive further progress in this field.