Published October 14, 2024
| Version v1
Dataset
Open
RNA phenotypes, xQTLs, xTWAS weights, and xTWAS results for Geuvadis and GTEx using Pantry
Creators
Description
This repository contains RNA phenotyping genetic analysis results for 55 human tissue datasets using Pantry. It includes RNA phenotypes, covariates, cis-QTL results from tensorQTL, and weights and associations for multimodal transcriptome-wide association study (xTWAS) results using FUSION, for six RNA modalities, for Geuvadis and 54 GTEx tissues. The xTWAS data covers 114 traits using GWAS data from Publicly available GWAS summary statistics, harmonized and imputed to GTEx v8' variant reference. For more information, see the publication "Multimodal analysis of RNA sequencing data powers discovery of complex trait genetics".
Files
README.md
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Additional details
Related works
- Is source of
- Preprint: 10.1101/2024.05.14.594051 (DOI)
- Software: 10.5281/zenodo.13922024 (DOI)
Funding
- National Institute of General Medical Sciences
- Haplotype-aware models of gene and isoform expression with application to genetic studies of disease in diverse populations R01GM140287
- National Institute on Drug Abuse
- Center for Genetic Studies of Drug Abuse in Outbred Rats P50DA037844
Software
- Repository URL
- https://github.com/PejLab/Pantry
- Programming language
- Snakemake, Python, R