Published September 30, 2024 | Version https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue9,Article19.pdf
Journal article Open

Clinical Profile of Post-Menopausal Women with Urinary Tract Infection

  • 1. Post Graduate Trainee, Department of General Medicine, GMCH, Guwahati
  • 2. Professor, Department of General Medicine, GMCH, Guwahati
  • 3. Scientist C, Multidisciplinary Research Unit, GMCH, Guwahati

Description

Background: An annual issue for millions of people worldwide are urinary tract infections (UTIs), which are a frequent and chronic medical condition. The most prevalent bacterial illness among women overall, and among postmenopausal women specifically, is urinary tract infection (UTI). Regarding age and general state, two groups of elderly women with recurrent UTIs should be distinguished: elderly institutionalized women with or without a catheter and healthy, young postmenopausal women between the ages of 50 and 70 who are neither institutionalized nor catheterized. Methods: A study population of 134 post-menopausal women, attending OPD or admitted to Department of General Medicine, Gauhati Medical College and Hospital and study duration was from December 2023 to July 2024. The co-morbidities, recurrence of UTI and the type of organisms isolated from urine sample were studied. Data were analysed using PRISM software, version 8.0. Results: The most common age group of prevalence of UTI in the most menopausal female was in 44-52 years (44%). The overall the recurrence rate was 41.3% and the rate was highest in the >80 years age group (77%). There was statistically significant association between diabetes mellitus and UTI recurrence with p value of 0.03. The most common organism isolated was E. coli 76.8%, in urine cultures. It was also responsible for adverse outcomes. Conclusion: The study revealed a higher recurrence rate with advanced age among postmenopausal women. There was two times more risk of developing UTI in patients with Diabetes Mellitus. E. coli was the most common organism responsible.

 

 

 

Abstract (English)

Background: An annual issue for millions of people worldwide are urinary tract infections (UTIs), which are a frequent and chronic medical condition. The most prevalent bacterial illness among women overall, and among postmenopausal women specifically, is urinary tract infection (UTI). Regarding age and general state, two groups of elderly women with recurrent UTIs should be distinguished: elderly institutionalized women with or without a catheter and healthy, young postmenopausal women between the ages of 50 and 70 who are neither institutionalized nor catheterized. Methods: A study population of 134 post-menopausal women, attending OPD or admitted to Department of General Medicine, Gauhati Medical College and Hospital and study duration was from December 2023 to July 2024. The co-morbidities, recurrence of UTI and the type of organisms isolated from urine sample were studied. Data were analysed using PRISM software, version 8.0. Results: The most common age group of prevalence of UTI in the most menopausal female was in 44-52 years (44%). The overall the recurrence rate was 41.3% and the rate was highest in the >80 years age group (77%). There was statistically significant association between diabetes mellitus and UTI recurrence with p value of 0.03. The most common organism isolated was E. coli 76.8%, in urine cultures. It was also responsible for adverse outcomes. Conclusion: The study revealed a higher recurrence rate with advanced age among postmenopausal women. There was two times more risk of developing UTI in patients with Diabetes Mellitus. E. coli was the most common organism responsible.

 

 

 

Files

IJPCR,Vol16,Issue9,Article19.pdf

Files (348.9 kB)

Name Size Download all
md5:9424aec76a9bb7f698e7a33bd63fd14f
348.9 kB Preview Download

Additional details

Dates

Accepted
2024-08-26

References

  • 1. McLellan LK, Hunstad DA. Urinary Tract Infection: Pathogenesis and Outlook. Trends Mol Med. 2016 Nov; 22(11):946–57. 2. Raz R, Gennesin Y, Wasser J, Stoler Z, Rosenfeld S, Rottensterich E, et al. Recurrent Urinary Tract Infections in Postmenopausal Women. Clin Infect Dis. 2000 Jan 1; 30(1):152–6. 3. Al Lawati H, Blair BM, Larnard J. Urinary Tract Infections: Core Curriculum 2024. Am J Kidney Dis. 2024 Jan; 83(1):90–100. 4. Kaur R, Kaur R. Symptoms, risk factors, diagnosis and treatment of urinary tract infections. Postgrad Med J. 2021 Dec 1; 97(1154):803– 12. 5. Hooton TM. Uncomplicated Urinary Tract Infection. N Engl J Med. 2012 Mar 15; 366(11):1028–37. 6. Salvatore S, Salvatore S, Cattoni E, Siesto G, Serati M, Sorice P, et al. Urinary tract infections in women. Eur J Obstet Gynecol Reprod Biol. 2011 Jun; 156(2):131–6. 7. Funfstuck R, Nicolle LE, Hanefeld M, Naber KG. Urinary tract infection in patients with diabetes mellitus. Clin Nephrol. 2012 Jan 1; 77(01):40–8. 8. Wang MC, Tseng CC, Wu AB, Lin WH, Teng CH, Yan JJ, et al. Bacterial characteristics and glycemic control in diabetic patients with Escherichia coli urinary tract infection. J Microbiol Immunol Infect. 2013 Feb; 46(1):24–9. 9. Hu KK, Boyko EJ, Scholes D, Normand E, Chen CL, Grafton J, et al. Risk Factors for Urinary Tract Infections in Postmenopausal Women. Arch Intern Med. 2004 May 10; 164(9):989. 10. Raz R. Urinary Tract Infection in Postmenopausal Women. Korean J Urol. 2011; 52(12):801. 11. Jung C, Brubaker L. The etiology and management of recurrent urinary tract infections in postmenopausal women. Climacteric. 2019 May 4; 22(3):242–9. 12. Saliba W, Nitzan O, Chazan B, Elias M. Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management. Diabetes Metab Syndr Obes Targets Ther. 2015 Feb; 129. 13. Lim JH, Cho JH, Lee JH, Park YJ, Jin S, Park GY, et al. Risk Factors for Recurrent Urinary Tract Infection in Kidney Transplant Recipients. Transplant Proc. 2013 May; 45(4):1584– 9. 14. Flores-Mireles AL, Walker JN, Caparon M, Hultgren SJ. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015 May; 13(5): 269–84. 15. Klein RD, Hultgren SJ. Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies. Nat Rev Microbiol. 2020 Apr; 18(4):211–26.