Evaluation of Iron Deficiency Anemia as a Risk Factor for Febrile Seizures: A Prospective Study
Creators
- 1. Assistant Professor, Dept. of Pediatrics, Venkateshwara Institute of Medical Sciences, Gajraula
- 2. Assistant Professor, Dept. of Pediatrics, GMC Rajouri
- 3. Senior Resident, Dept. of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh
- 4. Assistant Professor, Dept. of ENT, Teerthankar Mahaveer Medical College & Research Center, Moradabad
Description
Febrile seizure (FS) is a common cause of seizure in young children and occurring in 3-4% children under 5 years of age. Iron deficiency is reported as commonest micro-nutritional deficiency worldwide and has been associated with febrile seizures. The aim was to evaluate role of Iron deficiency as a risk factor of febrile seizure. Methodology: 170 children (6m – 5 years) were included in the study. 70 cases had febrile seizure as defined by International League Against Epilepsy and rest 100 controls had short history of febrile illness (< 3 days) without seizures. Anemia was defined as decrease of the Hb <11gm%, and serum ferritin <12ng/ml. Discrete variables are expressed as counts (%) and compared using the Chi-square tests, significance is set at p < 0.05. Observations: In the present study, 34.3% cases belong to 6-16 months age group and male to female ratio in cases was 1.69:1. 65.7% of cases and 45% of controls were iron deficient. On correlating iron deficiency with gender, male preponderance was observed in children with febrile seizure. The study observed 65.7% cases of FS had iron deficiency as compared to 45% of control group. (OR-2.34; p<0.05). Also, there was statistically significant association between recurrence of FS and iron deficiency. Conclusion: Early detection and timely correction of iron deficiency may be helpful for prevention of febrile seizures in children of this age group.
Abstract (English)
Febrile seizure (FS) is a common cause of seizure in young children and occurring in 3-4% children under 5 years of age. Iron deficiency is reported as commonest micro-nutritional deficiency worldwide and has been associated with febrile seizures. The aim was to evaluate role of Iron deficiency as a risk factor of febrile seizure. Methodology: 170 children (6m – 5 years) were included in the study. 70 cases had febrile seizure as defined by International League Against Epilepsy and rest 100 controls had short history of febrile illness (< 3 days) without seizures. Anemia was defined as decrease of the Hb <11gm%, and serum ferritin <12ng/ml. Discrete variables are expressed as counts (%) and compared using the Chi-square tests, significance is set at p < 0.05. Observations: In the present study, 34.3% cases belong to 6-16 months age group and male to female ratio in cases was 1.69:1. 65.7% of cases and 45% of controls were iron deficient. On correlating iron deficiency with gender, male preponderance was observed in children with febrile seizure. The study observed 65.7% cases of FS had iron deficiency as compared to 45% of control group. (OR-2.34; p<0.05). Also, there was statistically significant association between recurrence of FS and iron deficiency. Conclusion: Early detection and timely correction of iron deficiency may be helpful for prevention of febrile seizures in children of this age group.
Files
IJPCR,Vol16,Issue9,Article6.pdf
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Additional details
Dates
- Accepted
-
2024-08-22
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue9,Article6.pdf
- Development Status
- Active
References
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