CRITERION VALIDATION OF 'ASD RELATED ITEMS' IN INCLENNDST – RESEARCH FORM AGAINST AIIMS MODIFIED INDT-ASD AS GOLD STANDARD
Contributors
- 1. 1. Emeritus Professor in Allied Health, Noorul Islam Centre for Higher Education (NICHE), Deemed-to-be University, Kumarakovil, Kanyakumari District &Director, NIMS-Spectrum-CDRC, Aralumoodu, Tvpm. 2. IAP Fellowship Trainee in Developmental & Behaviroual Pediatrics, NIMS-Spectrum-CDRC, Aralumoodu, Tvpm 3. IAP Fellowship in Developmental Nurse Counsellor Trainee, NIMS-Spectrum-CDRC, Aralumoodu, Tvpm 4.Formerly Associate Professor & Clinical Epidemiologist, Department of Community Medicine, GMC, Tvpm. 5. Senior Developmental Therapist, NIMS-Spectrum-CDRC, Aralumoodu,Tvpm 6. Developmental Therapist, NIMS-Spectrum-CDRC, Aralumoodu,Tvpm
Description
Abstract:
Autism Spectrum Disorder (ASD) is an important
developmental disorder worldwide with a
prevalence of 0.09% - 1.07%, in the Southeast
Asia population including India.
Objectives: The primary objective of the study
was criterion validation of ‘ASD-related items’
in NDST as a screening tool for ASD against
AIIMS-modified INDT-ASD as gold standard
and to calculate sensitivity, specificity, predictive
values, diagnostic accuracy, and likelihood ratios.
Methodology: This is a descriptive study -
diagnostic test evaluation, which was carried
out from January- July 2022, at NIMS Spectrum
- CDRC, Thiruvananthapuram, a tertiary care
center for children with neurodevelopmental
problems. Fifty children, who came to CDRC
with suspected developmental problems were
screened with ASD-related items in NDST by
an experienced Developmental therapist and
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Additional details
Dates
- Accepted
-
2024-09-29
References
- 1. Autism Data Visualization Tool. Available from URL: https://www.cdc.gov/ncbddd/autism/data/ index.html Accessed on 08/08/2024. 2. Hossain MD, Ahmed HU, Jalal Uddin MM, Chowdhury WA, Iqbal MS, Kabir RI, Chowdhury IA, Aftab A, Datta PG, Rabbani G, Hossain SW. Autism Spectrum Disorders (ASD) in South Asia: a systematic review. BMC psychiatry. 2017 Dec;17:1-7. 3. Arora NK, Nair MKC, Gulati S, et.al. Neurodevelopmental disorders in children aged 2-9 years: Population-based burden estimates across five regions in India. PLoS Med. 2018 Jul 24;15(7):e1002615. doi: 10.1371/journal.pmed.1002615. 4. George B, Padmam MS, Nair MK, Leena ML, Russell PS. CDC Kerala 14: Early child care practices at home among children (2-6 y) with autism--a case-control study. Indian J Pediatr. 2014 Dec;81 Suppl2:S138-41. doi: 10.1007/s12098-014-1602-5. 5. Juneja M, Mishra D, Russell PS, Gulati S, DeshmukhV, Tudu P, Sagar R, Silberberg D, Bhutani VK, Pinto JM, Durkin M, Pandey RM, Nair MKC, Arora NK; INCLEN Study Group. INCLEN Diagnostic Tool for Autism Spectrum Disorder (INDT-ASD): development and validation. Indian Pediatr. 2014 May;51(5):359-65. doi: 10.1007/s13312-014-0417-9. 6. Gulati S, Kaushik JS, Saini L, Sondhi V, Madaan P, Arora NK, Pandey RM, JauhariP, Manokaran RK, Sapra S, Sharma S, Paul VK, Sagar R. Development and validation of DSM-5 based diagnostic tool for children with Autism spectrum disorder. PLoS One. 2019 Mar 13;14(3):e0213242. Doi:10.1371/journal.pone.0213242. 7. Chauhan A, Sahu JK, Jaiswal N, Kumar K, Agarwal A, Kaur J, Singh S, Singh M. Prevalence of autism spectrum disorder in Indian children: A systematic review and meta-analysis. Neurology India. 2019 Jan 1;67(1):100.