Clinical Profile of Acute Poisoning Cases and their Outcomes
Authors/Creators
- 1. Tutor, Department of pharmacology, Darbhanga medical college, Laheriasarai, Darbhanga, Bihar, India
- 2. Senior Resident, Department of Obstetrics and Gynecology, Darbhanga medical college and Hospital, Laheriasarai, Darbhanga, Bihar, India
- 3. Assistant Professor, Department of pharmacology, Darbhanga medical college, Laheriasarai, Darbhanga, Bihar, India
- 4. Professor, Department of pharmacology, Darbhanga medical college, Laheriasarai, Darbhanga, Bihar, India
Description
Introduction: The present study was done to describe the incidence, nature, severity, and treatment outcome trends associated with acute poisoning cases presenting to our hospital. Methodology: This prospective observational study was conducted by including patients who were admitted to the emergency department, Darbhanga Medical College, Laheriasarai, Darbhanga, Bihar, India with a clinical diagnosis of acute poisoning from January 2021 till June 2021. Their socio-demographic variables and poison comsumed was noted. Results: In the present study, 172 patients were included. Mean age of the patients was 27.45 years, ranging from 12 to 71 years. The sample consisted of 68% males and 61% were had an urban residence. Among all cases, 64% were suicidal cases and rest were accidental poisonings. Recovery and discharge were observed in 73%, 19% died (N=32) and 8% left against medical advice. The most common poison consumed was organophosphate (n=36). Next most common was methanol poisoning (n=27) and aluminium phosphide (n=22). Forty percent arrived at the hospital within 2 hours of poison consumption. It was observed that patients from older age group (p value < 0.05) and those presenting to the hospital after 4 to 6hours (p value < 0.05) were found to be associated with poor outcomes. Conclusions: Our study found that patients of older age group and those arriving late to the hospital were found to have significantly poor outcomes. Also, we observed high case fatality in poisonings with aluminium phosphide, organophosphate, phenyl and insecticides.
Abstract (English)
Introduction: The present study was done to describe the incidence, nature, severity, and treatment outcome trends associated with acute poisoning cases presenting to our hospital. Methodology: This prospective observational study was conducted by including patients who were admitted to the emergency department, Darbhanga Medical College, Laheriasarai, Darbhanga, Bihar, India with a clinical diagnosis of acute poisoning from January 2021 till June 2021. Their socio-demographic variables and poison comsumed was noted. Results: In the present study, 172 patients were included. Mean age of the patients was 27.45 years, ranging from 12 to 71 years. The sample consisted of 68% males and 61% were had an urban residence. Among all cases, 64% were suicidal cases and rest were accidental poisonings. Recovery and discharge were observed in 73%, 19% died (N=32) and 8% left against medical advice. The most common poison consumed was organophosphate (n=36). Next most common was methanol poisoning (n=27) and aluminium phosphide (n=22). Forty percent arrived at the hospital within 2 hours of poison consumption. It was observed that patients from older age group (p value < 0.05) and those presenting to the hospital after 4 to 6hours (p value < 0.05) were found to be associated with poor outcomes. Conclusions: Our study found that patients of older age group and those arriving late to the hospital were found to have significantly poor outcomes. Also, we observed high case fatality in poisonings with aluminium phosphide, organophosphate, phenyl and insecticides.
Files
IJPCR,Vol14,Issue1,Article29.pdf
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Additional details
Dates
- Accepted
-
2021-12-28
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue1,Article29.pdf
- Development Status
- Active
References
- 1. World Health Organization – International Programme on Chemical Safety: Poisoning Prevention and Management. Available from: http:// www.who.int/ipcs/poisons/en/. [Last accessed on 2021 Oct 4]. 2. Accidents in India. In: Accidental Deaths and Suicides in India. Ch. 1. New Delhi: National Crime Records Bureau, Ministry of Home Affairs, Government of India; 2014. Available from: http://www.ncrb.gov.in/ StatPublications/ADSI/ADSI2014/chapter‐1%20accidents.pdf. [Last accessed on 2021 Oct 4]. 3. Chatterjee S, Verma VK, Hazra A, Pal J. An observational study on acute poisoning in a tertiary care hospital in West Bengal, India. Perspectives in clinical research. 2020;11(2):75. 4. Anandabaskar N, Murugan R, Selvaraj N, Jayaraman M, Rajamohammad MA, Kagne RN. A retrospective analysis of acute poisoning cases admitted to a tertiary care hospital in South. Int J Basic Clin Pharmacol 2019; 8:2271-7. 5. Mathew R, Jamshed N, Aggarwal P, Patel S, Pandey RM. Profile of acute poisoning cases and their outcome in a teaching hospital of north India. J Family Med Prim Care 2019; 8:3935-9. 6. Sarkar D, Shaheduzzaman M, Hossain MI, Ahmed M, Mohammad N, Basher A. Spectrum of acute pharmaceutical and chemical poisoning in northern Bangladesh. Asia Pac J Med Toxicol 2013; 2:2‐5. 7. Vanishree, Chavan VR, Arshad M, Raghunandan M, Faizuddin. A study on pattern of acute poisoning in an emergency department of a tertiary care hospital. Asian J Pharm Clin Res 2016; 9:361‐3. 8. Celine TM, Antony J. A profile of acute poisonings: A retrospective study. J Sci Soc 2015; 42:156‐60. 9. Ramesha KN, Rao KB, Kumar GS. Pattern and outcome of acute poisoning cases in a tertiary care hospital in Karnataka, India. Indian J Crit Care Med 2009; 13:152‐5. 10. Singh S, Sharma BK, Wahi PL, Anand BS, Chugh KS. Spectrum of acute poisoning in adults (10-year experience). J Assoc Physicians India 1984; 32:561‐3. 11. Srinivas Rao CH, Venkateswarlu V, Surender T, Eddleston M, Buckley NA. Pesticide poisoning in South India: Opportunities for prevention and improved medical management. Trop Med Int Health 2005; 10:581‐8.