A Study on CT Evaluation of Colorectal Lesions, Correlation with Histopathology
Creators
- 1. Senior Resident, Department of Radiodiagnosis, GSL Medical College, Rajahmundry.
- 2. Associate Professor, Department of Radiodiagnosis, GSL Medical College, Rajahmundry.
- 3. Professor & Head, Department of Radiodiagnosis, GSL Medical College, Rajahmundry.
- 4. Central Research Laboratory, GSL Medical College, Rajahmundry.
Description
Introduction: In developed nations, colorectal cancer ranks second in cancer-related mortality, emphasizing its public health impact. Early detection and advanced treatment are vital for mortality reduction. CT scans, increasingly preferred for diagnosis, aid in assessing colorectal cancer (CRC). Histopathological examination (HPE) complements this by confirming diagnosis, guiding treatment, and correlating CT staging with histopathological examination results. Methods: In a cross-sectional study, patients referred to radiology with symptomatic etiology, suspected large bowel lesions, or high-risk factors were included. Exclusion criteria encompassed contraindications to CT, absence of HPE correlation, biopsy refusal, or abnormal renal parameters. Preparatory procedures included fasting, medical history review, hydration, and contrast administration with subsequent imaging. Results: Thirty participants (mean age: 55.37 ± 15.82 years; male-female ratio: 1.15) were included. Abdominal pain was the predominant clinical presentation in benign and malignant cases, with common rectal involvement. Significant differences in attenuation pattern, thickness, and length correlated with histopathological examination. CT diagnosis effectively distinguished between benign and malignant lesions. Conclusion: CRC poses a significant global health burden, with an increasing incidence in India. Recent advancements in diagnosis include genetic studies and imaging techniques. CRC predominantly affects individuals aged 50 and above, with symptoms varying between benign and malignant lesions. CT demonstrates high sensitivity and specificity in detecting CRC, aiding in accurate diagnosis and treatment planning.
Abstract (English)
Introduction: In developed nations, colorectal cancer ranks second in cancer-related mortality, emphasizing its public health impact. Early detection and advanced treatment are vital for mortality reduction. CT scans, increasingly preferred for diagnosis, aid in assessing colorectal cancer (CRC). Histopathological examination (HPE) complements this by confirming diagnosis, guiding treatment, and correlating CT staging with histopathological examination results. Methods: In a cross-sectional study, patients referred to radiology with symptomatic etiology, suspected large bowel lesions, or high-risk factors were included. Exclusion criteria encompassed contraindications to CT, absence of HPE correlation, biopsy refusal, or abnormal renal parameters. Preparatory procedures included fasting, medical history review, hydration, and contrast administration with subsequent imaging. Results: Thirty participants (mean age: 55.37 ± 15.82 years; male-female ratio: 1.15) were included. Abdominal pain was the predominant clinical presentation in benign and malignant cases, with common rectal involvement. Significant differences in attenuation pattern, thickness, and length correlated with histopathological examination. CT diagnosis effectively distinguished between benign and malignant lesions. Conclusion: CRC poses a significant global health burden, with an increasing incidence in India. Recent advancements in diagnosis include genetic studies and imaging techniques. CRC predominantly affects individuals aged 50 and above, with symptoms varying between benign and malignant lesions. CT demonstrates high sensitivity and specificity in detecting CRC, aiding in accurate diagnosis and treatment planning.
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IJTPR,Vol14,Issue8,Article6.pdf
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Additional details
Dates
- Accepted
-
2024-07-25
Software
References
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