Comparative Evaluation of Serum Thyroid Profile in Between Different Stages of Chronic Renal Failure

Abstract:
Objective: This study aimed to evaluate the Serum Thyroid Profile in between different stages of Chronic Renal
Failure
Materials and Methods: 70 patients aged 18-60 years who were diagnosed as Chronic Kidney Disease on the
basis of e-GFR and 70 healthy individuals as controls. Overnight fasting venous blood samples were collected
from both groups for Thyroid Profile estimation. Urea and Creatinine estimation were also done to test for renal
function.
Results: Our study advances our knowledge thyroid hormone in CRF that these patients have decreased serum
T3 and serum T4 & increased serum TSH levels compared to different stages of CRF.
Conclusion: Alterations in thyroid hormone may underline many of the aspects of path-physiology and clinical
characteristics of CRF. It is worthwhile to check thyroid hormone and T3, T4 and TSH values frequently in
CRF patients during the course of the treatment and to treat them accordingly which will result in decreased
morbidity and mortality.
Keywords: Chronic Renal Failure, Thyroid Hormones, Hypothalamus Pituitary Glands, Glomerular Filtration
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