A Study of Vitamin D Estimation in Rheumatoid Arthritis Patients
Creators
- 1. Associate Professor, Department of Biochemistry, Banas Medical College and Research Institute, Palanpur, Gujarat, India
- 2. Assistant Professor, Department of Orthopaedics, Smt. NHL Medical College, Ahmedabad, Gujarat, India
- 3. Associate Professor, Department of Biochemistry, NAMO Medical Education and Research Institute, Silvassa, Dadra and Nagar Haveli, India
- 4. Assistant Professor, Department of Community Medicine, Banas Medical College and Research Institute, Palanpur, Gujarat, India
Description
Background: Vitamin D interacts with the immune system. Vitamin D deficiency is related with increase susceptibility and severity of autoimmune diseases like type 1 diabetes mellitus, multiple sclerosis, inflammatory bowel disease, systemic lupus erythematous (SLE) and rheumatoid arthritis. Objectives: 1) To study the role of vitamin D deficiency in rheumatoid arthritis patient 2) To study the demographic profile in in rheumatoid arthritis patients. Material & Method: In the present case control study, vitamin D was estimated in 70 patients of Rheumatoid arthritis and 70 healthy controls. Result: Mean Serum Vitamin D level was 21.78 ng/ml in rheumatoid arthritis patient’s case group, while 25.54 ng/ml in control group. Although Vitamin D deficiency or insufficiency was common in RA group of patients, the difference was not statistically significant (p>0.05) Prevalence of RA is higher among females as compared to males. Mean age in case group was 43.86 ± 12.017 years, while 40.57 ± 13.53 years in control group and maximum disease prevalence is between third and fourth decades. Conclusion: In this study we found that in RA patients, vitamin D deficiency is quite common, but not more common than in age and sex matched controls representative of the general population. Given the evidence regarding the role of vitamin D in overall health, clinicians should consider screening of RA patients to identify and address suboptimal vitamin D levels.
Abstract (English)
Background: Vitamin D interacts with the immune system. Vitamin D deficiency is related with increase susceptibility and severity of autoimmune diseases like type 1 diabetes mellitus, multiple sclerosis, inflammatory bowel disease, systemic lupus erythematous (SLE) and rheumatoid arthritis. Objectives: 1) To study the role of vitamin D deficiency in rheumatoid arthritis patient 2) To study the demographic profile in in rheumatoid arthritis patients. Material & Method: In the present case control study, vitamin D was estimated in 70 patients of Rheumatoid arthritis and 70 healthy controls. Result: Mean Serum Vitamin D level was 21.78 ng/ml in rheumatoid arthritis patient’s case group, while 25.54 ng/ml in control group. Although Vitamin D deficiency or insufficiency was common in RA group of patients, the difference was not statistically significant (p>0.05) Prevalence of RA is higher among females as compared to males. Mean age in case group was 43.86 ± 12.017 years, while 40.57 ± 13.53 years in control group and maximum disease prevalence is between third and fourth decades. Conclusion: In this study we found that in RA patients, vitamin D deficiency is quite common, but not more common than in age and sex matched controls representative of the general population. Given the evidence regarding the role of vitamin D in overall health, clinicians should consider screening of RA patients to identify and address suboptimal vitamin D levels.
Files
IJPCR,Vol14,Issue6,Article38.pdf
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Additional details
Dates
- Accepted
-
2022-06-10
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue6,Article38.pdf
- Development Status
- Active
References
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