Published 2005
| Version v1
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Antigenic and molecular characterization of rabies virus in Argentina
Description
(Uploaded by Plazi for the Bat Literature Project) The nucleoprotein genes of 54 human, domestic and wild animals rabies isolates obtained in Argentina between 1995 and 2002 were characterized using monoclonal antibodies and partial gene sequence analysis. The antigenic and genetic diversities of rabies virus in samples from bat and bat-related cases were studied, leading to the identification of five distinct genetic variants. Rabies viruses isolated from vampire bat related cases were very similar to each other, showing 98.9% overall similarity. Specific antigenic variants (AgV) were detected associated with different insectivorous bats species, in samples from Tadarida brasiliensis and Eumops patagonicus bats. In contrast, isolates from Myotis sp. and Histiotus sp. bats could not be matched to any antigenic type. Additionally, bat rabies cases were also detected in southern provinces previously considered rabies-free. Finally, two independent antigenic and genetic variants co-circulating in northern Argentina were found in isolates obtained from dogs and dog-related cases, suggesting two independent cycles of virus transmission.
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Additional details
Identifiers
- URL
- hash://md5/b0bb3f27ae8522ee5e989d8b3c42c3b1
- URN
- urn:lsid:zotero.org:groups:5435545:items:775YKYAM
- DOI
- 10.1016/j.virusres.2004.10.013
Biodiversity
- Class
- Mammalia
- Kingdom
- Animalia
- Order
- Chiroptera
- Phylum
- Chordata