Prospective Study to Evaluate Calcium and Vitamin D Deficiency in Elderly Rural Population and Effect of Calcium and Vitamin D Supplementation on Bone Mineral Density
Creators
- 1. Assistant Professor, Dept. of Orthopedics, Konaseema Institute of Medical Sciences (KIMS), Amalapuram, Andhra Pradesh 533201, India
- 2. Associate Professor, Dept. of Orthopedics, Konaseema Institute of Medical Sciences (KIMS), Amalapuram, Andhra Pradesh 533201, India
- 3. Post Graduate, Dept. of Orthopedics, Konaseema Institute of Medical Sciences (KIMS), Amalapuram, Andhra Pradesh 533201, India
Description
Background: Vitamin D is essential for humans for calcium homeostasis and bone health. Vitamin D deficiency causes osteoporosis and other musculoskeletal disorders. This study is aimed to evaluate the levels of vitamin D among the elderly males and post-menopausal females, and prevalence of vitamin D deficiency in Konaseema region. Materials and Methods: This correlational study was conducted on men and women above 50 years attending the hospital OPD in Konaseema Institute of Medical Sciences Hospital for a period of 2 years. Blood samples for serum 25-(OH) vitamin D, calcium and phosphorus were collected from the patients by venipuncture observing all safety and aseptic precautions. Data collected was analyzed for any correlation in the values between the biochemical parameters and vitamin D and calcium supplementation. Result: Our study found that Vitamin D levels and bone mass density are inversely related to age which is more evident in post-menopausal women due to steep fall in estrogen levels after menopause. In this study, the individuals are supplemented with calcium (calcium carbonate) 1000mg per day and 800 IU of vitamin D (daily dose), and they were followed up at 3rd, 6th, and 12th month. In the present study, following vitamin D supplementation in osteoporotic elderly people, there was a significant increase in the bone mineral density, analyzed by T scores. Our study mainly relied upon serum calcium, serum vitamin D levels and T scores, whose improved values were significant (p < 0.001). Our study follow up was done for 1 year in 3 phases (3rd, 6th, 12th months). Conclusion: The vitamin D deficiency is common in poor and lower middle class likely due to under nutrition. This study points out higher prevalence of Vitamin D inadequacy and low BMD in post-menopausal women and elderly persons in Konaseema region. It can be concluded with the recommendation that post-menopausal women and elderly males, especially from lower socioeconomic group in Konaseema region, should be administered vitamin D and calcium regularly.
Abstract (English)
Background: Vitamin D is essential for humans for calcium homeostasis and bone health. Vitamin D deficiency causes osteoporosis and other musculoskeletal disorders. This study is aimed to evaluate the levels of vitamin D among the elderly males and post-menopausal females, and prevalence of vitamin D deficiency in Konaseema region. Materials and Methods: This correlational study was conducted on men and women above 50 years attending the hospital OPD in Konaseema Institute of Medical Sciences Hospital for a period of 2 years. Blood samples for serum 25-(OH) vitamin D, calcium and phosphorus were collected from the patients by venipuncture observing all safety and aseptic precautions. Data collected was analyzed for any correlation in the values between the biochemical parameters and vitamin D and calcium supplementation. Result: Our study found that Vitamin D levels and bone mass density are inversely related to age which is more evident in post-menopausal women due to steep fall in estrogen levels after menopause. In this study, the individuals are supplemented with calcium (calcium carbonate) 1000mg per day and 800 IU of vitamin D (daily dose), and they were followed up at 3rd, 6th, and 12th month. In the present study, following vitamin D supplementation in osteoporotic elderly people, there was a significant increase in the bone mineral density, analyzed by T scores. Our study mainly relied upon serum calcium, serum vitamin D levels and T scores, whose improved values were significant (p < 0.001). Our study follow up was done for 1 year in 3 phases (3rd, 6th, 12th months). Conclusion: The vitamin D deficiency is common in poor and lower middle class likely due to under nutrition. This study points out higher prevalence of Vitamin D inadequacy and low BMD in post-menopausal women and elderly persons in Konaseema region. It can be concluded with the recommendation that post-menopausal women and elderly males, especially from lower socioeconomic group in Konaseema region, should be administered vitamin D and calcium regularly.
Files
IJPCR,Vol16,Issue8,Article55.pdf
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Additional details
Dates
- Accepted
-
2024-07-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue8,Article55.pdf
- Development Status
- Active
References
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