To Evaluate the Levels of Serum Calcium, Magnesium and Phosphorus in Hypothyroid Patients
Creators
- 1. M.Sc M.L.T Department of Biochemistry, Govt. Medical College and Rajindra Hospital, Patiala
- 2. Professor and Head, Department of Biochemistry, Govt. Medical College and Rajindra Hospital, Patiala
- 3. Biochemist, Department of Biochemistry, Govt. Medical College and Rajindra Hospital, Patiala
- 4. Assistant Professor, Department of Biochemistry, Govt. Medical College and Rajindra Hospital, Patiala
- 5. Associate Professor, Department of Biochemistry, Govt. Medical College and Rajindra Hospital, Patiala
- 6. Junior Resident, Department of Biochemistry, Govt. Medical College and Rajindra Hospital, Patiala
Description
Background: Hypothyroidism is one of the most prevalent forms of thyroid dysfunction in which the disease causes generalized slowing of metabolic processes. Thyroid dysfunction frequently disturbs mineral metabolism. The aim of the present study was to evaluate the levels of serum calcium, magnesium and phosphorus in patients with hypothyroidism. Materials and Methods: We conducted the present study on 100 lab-diagnosed cases of hypothyroidism based on the thyroid profile. 50 healthy controls were included in the study. We estimated serum calcium, magnesium and phosphorus in both cases and controls. Results: This study found that in people with hypothyroidism, the mean levels of calcium and magnesium in blood were significantly (p value<0.001) lower than in controls, while the levels of phosphorous were significantly (p value<0.001) higher. We found a significant negative correlation between both serum calcium and magnesium and serum TSH levels, and a significant positive correlation between serum phosphorous and serum TSH levels. Conclusion: The current study concluded that hypothyroidism alters the metabolism of minerals. Estimation of these minerals in hypothyroid patients will be of great benefit in the prevention and treatment of subsequent clinical manifestations.
Abstract (English)
Background: Hypothyroidism is one of the most prevalent forms of thyroid dysfunction in which the disease causes generalized slowing of metabolic processes. Thyroid dysfunction frequently disturbs mineral metabolism. The aim of the present study was to evaluate the levels of serum calcium, magnesium and phosphorus in patients with hypothyroidism. Materials and Methods: We conducted the present study on 100 lab-diagnosed cases of hypothyroidism based on the thyroid profile. 50 healthy controls were included in the study. We estimated serum calcium, magnesium and phosphorus in both cases and controls. Results: This study found that in people with hypothyroidism, the mean levels of calcium and magnesium in blood were significantly (p value<0.001) lower than in controls, while the levels of phosphorous were significantly (p value<0.001) higher. We found a significant negative correlation between both serum calcium and magnesium and serum TSH levels, and a significant positive correlation between serum phosphorous and serum TSH levels. Conclusion: The current study concluded that hypothyroidism alters the metabolism of minerals. Estimation of these minerals in hypothyroid patients will be of great benefit in the prevention and treatment of subsequent clinical manifestations.
Files
IJPCR,Vol16,Issue8,Article10.pdf
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Additional details
Dates
- Accepted
-
2024-07-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue8,Article10.pdf
- Development Status
- Active
References
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