Diagnostic Accuracy of Cervical Pap Smear in Detecting Cervical Lesions: A Comparative Study
Authors/Creators
- 1. Associate Professor, Department of Obstetrics and Gynecology, Vendanta Institute of Medical Sciences, Palghar
Description
Background: Carcinoma of cervix is a preventable condition and considerable effort goes into detecting and treating the preinvasive disease. Since 1943, Pap smear cytology has been used for the screening of cervical cancer. Therefore, the present study was conducted to compare pap smear and histopathological findings of unhealthy cervix in tertiary care hospital. Methods: The present comparative cross-sectional study was carried among women who presented with various gynaecological complaints at Department of Obstetrics and Gynaecology of tertiary care centre during November 2019 to October 2020. Sample sizes of 108 participants were enrolled in study. The collected data were analyzed with proper statistical methods using MS excel 2016. Results: The majority of participants were with mean age of 37.48± 8.03 years and white discharge (58.33%) as the commonest complaint. Pap smear shows sensitivity of 86.67%, specificity of 83.33% with accuracy of 84.26% when compared to histological findings. Conclusions: The high specificity and sensitivity of pap smear indicated that pap smear has an important role in the diagnosis of cervical pathology.
Abstract (English)
Background: Carcinoma of cervix is a preventable condition and considerable effort goes into detecting and treating the preinvasive disease. Since 1943, Pap smear cytology has been used for the screening of cervical cancer. Therefore, the present study was conducted to compare pap smear and histopathological findings of unhealthy cervix in tertiary care hospital. Methods: The present comparative cross-sectional study was carried among women who presented with various gynaecological complaints at Department of Obstetrics and Gynaecology of tertiary care centre during November 2019 to October 2020. Sample sizes of 108 participants were enrolled in study. The collected data were analyzed with proper statistical methods using MS excel 2016. Results: The majority of participants were with mean age of 37.48± 8.03 years and white discharge (58.33%) as the commonest complaint. Pap smear shows sensitivity of 86.67%, specificity of 83.33% with accuracy of 84.26% when compared to histological findings. Conclusions: The high specificity and sensitivity of pap smear indicated that pap smear has an important role in the diagnosis of cervical pathology.
Files
IJPCR,Vol14,Issue7,Article126.pdf
Files
(297.6 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:328e6bc9423b7a45170e49b26a94aea1
|
297.6 kB | Preview Download |
Additional details
Dates
- Accepted
-
2022-06-25
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue7,Article126.pdf
- Development Status
- Active
References
- 1. Dasari P. Grossly abnormal cervix: evidence for using colposcopy in the absence of squamous intraepithelial lesion by conventional papanicolau test. Journal of Gynecologic Surgery. 2011 Mar 1;27(1):5-8. 2. Shobha T, Davuluri S. Cervical cytopathology: Evaluation of its efficacy in detecting cervical precancerous and cancerous lesions, as evidenced by colposcopic biopsy. Int J Sci Res 2016;5:378-84. 3. Mustafa RA, Santesso N, Khatib R, Mustafa AA, Wiercioch W, Kehar R, etal. Systematic reviews and metaanalyses of the accuracy of HPV tests, visual inspection with acetic acid, cytology, and colposcopy. Int J Gynaecol Obstet 2016; 132:259-65. 4. Singh SL, Dastur NA, Nanavat MS. A comparision of colposcopy and the Papanicolaou smear: sensitivity, specificity and predictive value. Bombay Hospital Journal. 2000 Jul;42 (3):447-51. 5. Anttila A, Ronco G, Clifford G, Bray F, Hakama M, Arbyn M, et al. Cervical Cancer Screening Programmes and policies in 18 European countries. Br J Cancer. 2004; 91:935-41. 6. Verma I, Jain V, Kaur T. Application of bethesda system for cervical cytology in unhealthy cervix. J Clin Diagn Res. 2014 Sep;8(9): OC26-30. 7. Suraiya UB, Ratnam SS, Rao KB, Arulkumar S. Cancer screening in gynecology. Obstetrics and gynecology. New Delhi: Orient Longman; 1994:454- 464. 8. Bobdey S, Sathwara J, Jain A, Balasubramaniam G. Burden of cervical cancer and role of screening in India. Indian J Med Paediatr Oncol. 2016;37(40);278-85. 9. Prasad D, Sinha A, Mishra U, Parween S, Raman RB, Goel N. Colposcopic evaluation of cervix in symptomatic women and its correlation with Pap smear. A prospective study at a tertiary care centre. Journal of Family Medicine and Primary Care. 2021 Aug ;10(8):2923. 10. Akhter S, Bari A, Hayat Z. Variability study between Pap smear, Colposcopy and Cervical Histopathology findings. J Pak Med Assoc. 2015 Dec 1;65(12):1295-9. 11. Pimple SA, Amin G, Goswami S, Shastri SS. Evaluation of colposcopy vs cytology as secondary test to triage women found positive on visual inspection test. Indian J Cancer. 2010 Jul-Sep; 47(3): 308-13. 12. Boicea A, Pătraşcu A, Surlin V, Iliescu D, Schenker M, Chiuţu L. Correlations between colposcopy and histologicresults from colposcopically directed biopsy in cervical precance rouslesions. Rom J Morphol Embryol. 2012; 53 (3 Suppl): 735-41. 13. Garg R, Desai R. Cytologic and colposcopic evaluation of all symptomatic women at the tertiary care centre. Int J Adv Med 2017; 4:799-804. 14. Kalyankar VY, Kalyankar BV, Gadappa SN, Kute S. Colposcopic evaluation of unhealthy cervix and it's correlation with Papanicolau smear in cervical cancer screening. Int J Reprod Contracept Obstet Gynecol 2017; 6:4959-65. 15. Singhal A, Raina RK, Verma S, Verma A. Predictive accuracy of cervical cytology and colposcopy in diagnosing premalignant and malignant cervical lesions: A hospital-based study from the sub-Himalayan region of Indian subcontinent. CHRISMED Journal of Health and Research. 2019 Jan 1;6(1):39-43. 16. Sayyah-Melli M, Rahmani V, Ouladsahebmadarek E, Jafari-Shobeiri M, Gharabaghi PM, Vahidi MN. Diagnostic value of pap smear and colposcopy in non-benign cervical lesions. morbidity and mortality. 2019; 7: 211-15. 17. Savitha TS, Sapna W. A comparison of pap smear, colposcopy and colposcopy directed biopsy in evaluation of unhealthy cervix. Journal of Evolution of Medical and Dental Sciences. 2015 Mar 12;4(21):3639-48.