Comparative Study of Incidence, Recurrence Rate and Conjunctival Autografing with intraoperative Mitomycin-C in Management of Pterygium
- 1. Senior Resident, Upgraded Department of Ophthalmology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar
- 2. Assistant Professor, Upgraded Department of Ophthalmology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar
- 3. Professor and Head of Department, Upgraded Department of Ophthalmology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar
Description
Background: Pterygium excision with CONJUNCTIVAL AUTOGRAFTING is very popular technique to prevent recurrence with very few side effects. This is being tried out with success in different country. Aims of the present series an attempt was made to do a comparative study between intraoperative application of Mitomycin-C (0.02 %) and conjuctival autografting and their effectiveness, effects and rate of recurrence in patients. Material and Methods: The study was carried out on 30 patients who presented to the Eye department at Darbhanga Medical College and Hospital, Laheriasarai during the period from July 2019 to September 2020 and was analysed retrospectively. Efforts were made to select patients with pterygium. Selected patients were divided into two groups Group I and Group II. The statistical calculations show standard error of difference is 10.6, whereas observed difference (13.33 – 6.66) was 6.67. The observed difference between the two groups is less than twice the S.E. of difference i.e. 2 × 10.6. Therefore, observed difference between recurrence rates was not significant. Results: It was found that pterygium was more prevalent in between 3rd and 5th decade and beyond this range of age the incidence declines. The disease was more common in males than females. In symptomatology growth of red mass or fleshy mass was the predominant presenting symptom. This was followed by redness and irritation of the eye. In most of the patients improvement of visual acuity occurred after pterygium surgery. In group one patients, (conjunctival autografting) recurrence rate was 6.66 % (one out of fifteen). In group two patients, (intra-operative application of Mitomycin-c) there was 13.33% (two out of fifteen) recurrence rate. When recurrence rates of two groups were compared statistically, the difference was not significant. Conclusion: So it was concluded that either excision of pterygium with bare sclera technique along with conjunctival autograft or intra-operative application of Mitomycin-c (0.02 %) for 3 minutes are both equally effective adjuncts to prevent recurrence in pterygium surgery.
Abstract (English)
Background: Pterygium excision with CONJUNCTIVAL AUTOGRAFTING is very popular technique to prevent recurrence with very few side effects. This is being tried out with success in different country. Aims of the present series an attempt was made to do a comparative study between intraoperative application of Mitomycin-C (0.02 %) and conjuctival autografting and their effectiveness, effects and rate of recurrence in patients. Material and Methods: The study was carried out on 30 patients who presented to the Eye department at Darbhanga Medical College and Hospital, Laheriasarai during the period from July 2019 to September 2020 and was analysed retrospectively. Efforts were made to select patients with pterygium. Selected patients were divided into two groups Group I and Group II. The statistical calculations show standard error of difference is 10.6, whereas observed difference (13.33 – 6.66) was 6.67. The observed difference between the two groups is less than twice the S.E. of difference i.e. 2 × 10.6. Therefore, observed difference between recurrence rates was not significant. Results: It was found that pterygium was more prevalent in between 3rd and 5th decade and beyond this range of age the incidence declines. The disease was more common in males than females. In symptomatology growth of red mass or fleshy mass was the predominant presenting symptom. This was followed by redness and irritation of the eye. In most of the patients improvement of visual acuity occurred after pterygium surgery. In group one patients, (conjunctival autografting) recurrence rate was 6.66 % (one out of fifteen). In group two patients, (intra-operative application of Mitomycin-c) there was 13.33% (two out of fifteen) recurrence rate. When recurrence rates of two groups were compared statistically, the difference was not significant. Conclusion: So it was concluded that either excision of pterygium with bare sclera technique along with conjunctival autograft or intra-operative application of Mitomycin-c (0.02 %) for 3 minutes are both equally effective adjuncts to prevent recurrence in pterygium surgery.
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IJPCR,Vol14,Issue7,Article94.pdf
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Additional details
Dates
- Accepted
-
2022-06-05
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue7,Article94.pdf
- Development Status
- Active
References
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