Single Centric Hospital Based Observational Prospective Assessment of Clinico-Laboratory Profile of Seropositive Celiac Diseases in Severe Acute Malnutrition
Authors/Creators
- 1. Senior Resident, Department of Pediatrics, Chacha Nehru Bal Chikitsalaya, Lady Hardinge Medical College, Delhi, India
Description
Aim: To study clinico-laboratory profile of seropositive Celiac Diseases in Severe Acute Malnutrition. Material & Methods: The present study was single centric hospital based observational prospective study, conducted at Department of Pediatrics, Chacha Nehru Bal Chikitsalaya, Lady Hardinge Medical College, Delhi, India. The study was conducted over a period of one year. All the children of 1-5 years age group suffering from Severe Acute Malnutrition (SAM) admitted in Department of Pediatrics. Total 100 children with Severe Acute Malnutrition in age group 1-5 years, admitted in MTC were enrolled and screened for celiac serology. Out of these 100 cases celiac serology was positive in 25 cases with sero-positivity of 25%. Results: While mean MUAC was 11.88±1.47 v/s 11.38±1.14. The difference in MUAC in seronegative and seropositive cases was statistically insignificant (p-value>0.5). Total no. of cases in form of Z-score (<-2SD, <-3SD) in seronegative group and seropositive group were 2,73 and 0,25 respectively. This difference in sero-negative and sero-positive cases was statistically insignificant (P-value= >0.05). Conclusions: Recurrent diarrhoea and blood in stool were common presenting feature on admission in celiac seropositive patients suffering from severe acute malnutrition. Vit. B12 and Folic acid deficiency were also observed as a common finding in seropositive patients.
Abstract (English)
Aim: To study clinico-laboratory profile of seropositive Celiac Diseases in Severe Acute Malnutrition. Material & Methods: The present study was single centric hospital based observational prospective study, conducted at Department of Pediatrics, Chacha Nehru Bal Chikitsalaya, Lady Hardinge Medical College, Delhi, India. The study was conducted over a period of one year. All the children of 1-5 years age group suffering from Severe Acute Malnutrition (SAM) admitted in Department of Pediatrics. Total 100 children with Severe Acute Malnutrition in age group 1-5 years, admitted in MTC were enrolled and screened for celiac serology. Out of these 100 cases celiac serology was positive in 25 cases with sero-positivity of 25%. Results: While mean MUAC was 11.88±1.47 v/s 11.38±1.14. The difference in MUAC in seronegative and seropositive cases was statistically insignificant (p-value>0.5). Total no. of cases in form of Z-score (<-2SD, <-3SD) in seronegative group and seropositive group were 2,73 and 0,25 respectively. This difference in sero-negative and sero-positive cases was statistically insignificant (P-value= >0.05). Conclusions: Recurrent diarrhoea and blood in stool were common presenting feature on admission in celiac seropositive patients suffering from severe acute malnutrition. Vit. B12 and Folic acid deficiency were also observed as a common finding in seropositive patients.
Files
IJPCR,Vol14,Issue7,Article69.pdf
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Additional details
Dates
- Accepted
-
2022-07-10
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue7,Article69.pdf
- Development Status
- Active
References
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