Breast Mass Evaluation with Strain Elastography: A Prospective Cohort Study
Creators
- 1. M.D. (Radio-Diagnosis), SDMCMS & H, Senior Resident, Department of RadioDiagnosis, BMIMS and Hospital (VIMS), Pawapuri, Nalanda, Bihar, India
- 2. Professor & HOD, Department of Radio-Diagnosis, SDMCMS & H, Dharwad, Karnataka, India
- 3. Associate Professor Department of Paediatrics, BMIMS & H, Pawapuri, Nalanda, Bihar, India
Description
Introduction: Breast cancer is the most common cancer in the world and is one of the most common causes of morbidity and mortality. Hence, early detection by non- invasive technique is required without causing discomfort to patients which brings forth the role of real time breast elastography, a new method to assess the stiffness of any breast mass. Among different Elastographic methods we have used the strain ratio which is a semiquantitative method. Aims and Objectives: To differentiate benign breast masses from malignant ones , to correlate it with pathological investigations done and to know the sensitivity, specificity , positive predictive value, negative predictive value and accuracy of real time elastography for breast lesions. Material and Methods: Sample of 100 patients presenting with breast lump on which Elastographic sonography was done in Radiology department during the period, January 2018 to December 2018 at SDM Medical College and Hospital, Dharwad, Karnataka. Strain ratio were calculated and a cut off ratio of 3 was taken. A ratio above 3 was considered positive for malignancy and below 3 was considered to be benign. These findings were correlated with pathological investigations findings. Results: Out of 100 patients examined sonographically with breast lumps, 45 were malignant cases and 55 were benign cases. Sensitivity, specificity, PPV and NPV were 87%, 91% and 89% and 89% respectively. Significant correlation between Strain ratio and pathological outcome were found. Mean strain ratio for malignant lesions was 3.55 +\-1.46 m\s and that for benign lesions were 1.86 +\-1.32m\s. Conclusions: In our studies sensitivity, specificity, PPV, NPV and accuracy of strain elastography were good. So we can conclude that Strain elastography is very helpful in screening and diagnosing the malignant breast lesions, hence decreasing the need of biopsies to diagnose malignant lesions.
Abstract (English)
Introduction: Breast cancer is the most common cancer in the world and is one of the most common causes of morbidity and mortality. Hence, early detection by non- invasive technique is required without causing discomfort to patients which brings forth the role of real time breast elastography, a new method to assess the stiffness of any breast mass. Among different Elastographic methods we have used the strain ratio which is a semiquantitative method. Aims and Objectives: To differentiate benign breast masses from malignant ones , to correlate it with pathological investigations done and to know the sensitivity, specificity , positive predictive value, negative predictive value and accuracy of real time elastography for breast lesions. Material and Methods: Sample of 100 patients presenting with breast lump on which Elastographic sonography was done in Radiology department during the period, January 2018 to December 2018 at SDM Medical College and Hospital, Dharwad, Karnataka. Strain ratio were calculated and a cut off ratio of 3 was taken. A ratio above 3 was considered positive for malignancy and below 3 was considered to be benign. These findings were correlated with pathological investigations findings. Results: Out of 100 patients examined sonographically with breast lumps, 45 were malignant cases and 55 were benign cases. Sensitivity, specificity, PPV and NPV were 87%, 91% and 89% and 89% respectively. Significant correlation between Strain ratio and pathological outcome were found. Mean strain ratio for malignant lesions was 3.55 +\-1.46 m\s and that for benign lesions were 1.86 +\-1.32m\s. Conclusions: In our studies sensitivity, specificity, PPV, NPV and accuracy of strain elastography were good. So we can conclude that Strain elastography is very helpful in screening and diagnosing the malignant breast lesions, hence decreasing the need of biopsies to diagnose malignant lesions.
Files
IJPCR,Vol14,Issue8,Article15.pdf
Files
(1.5 MB)
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Additional details
Dates
- Accepted
-
2022-07-03
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue8,Article15.pdf
- Development Status
- Active
References
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