Published October 31, 2022 | Version https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue10,Article110.pdf
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Evaluation of Histopathological Reports of Abnormal Uterine Bleeding in Women at Tertiary Care Centre

  • 1. Associate Professor, Department of Obstetrics and Gynecology, Mediciti Institute of Medical Sciences, Ghapur, Medchal, Telangana, India
  • 2. Third Year, Postgraduate, Department of Obstetrics and Gynecology, Mediciti Institute of Medical Sciences, Ghapur, Medchal, Telangana, India

Description

Background: Abnormal uterine bleeding (AUB) which is a significant clinical entity and its subgroup, heavy menstrual bleeding (HMB), are common conditions having a significant impact on the physical, social, emotional and/or material quality of life of the affected 14–25% of women of reproductive age. Aim of the Study: To evaluate histopathological reports of abnormal uterine bleeding in women at tertiary care centres. Methodology: The retrospective cohort study was carried out from June 2020 to June 2022 in the Department of Obstetrics and Gynecology at a tertiary medical teaching hospital at Mediciti Institute of Medical Sciences, Medchal. Medical records of 100 cases of AUB were retrieved. A detailed history was taken and investigations were carried out. Results: The age group of 36-50 years was commonly associated with AUB. Maximum no. of women 45 cases were para 2 (45 %) while 4 cases (4 %) were nulliparous, 1 case (1 %) was para 1, other 37 women were para 3 and the remaining 10 women were para 4 or more. Management was done by medical and surgical approaches for these women. D and C alone or D and C followed by hysterectomy was the surgical approach. Majorly 82 cases (82 %) were associated with secretory endometrium on histopathology and 18 (18 %) cases were associated with the proliferative type of endometrium. Conclusion: The majority of endometrium was revealed by histopathology in the secretory phase and hysterectomy remained the commonest method of intervention.

 

 

 

Abstract (English)

Background: Abnormal uterine bleeding (AUB) which is a significant clinical entity and its subgroup, heavy menstrual bleeding (HMB), are common conditions having a significant impact on the physical, social, emotional and/or material quality of life of the affected 14–25% of women of reproductive age. Aim of the Study: To evaluate histopathological reports of abnormal uterine bleeding in women at tertiary care centres. Methodology: The retrospective cohort study was carried out from June 2020 to June 2022 in the Department of Obstetrics and Gynecology at a tertiary medical teaching hospital at Mediciti Institute of Medical Sciences, Medchal. Medical records of 100 cases of AUB were retrieved. A detailed history was taken and investigations were carried out. Results: The age group of 36-50 years was commonly associated with AUB. Maximum no. of women 45 cases were para 2 (45 %) while 4 cases (4 %) were nulliparous, 1 case (1 %) was para 1, other 37 women were para 3 and the remaining 10 women were para 4 or more. Management was done by medical and surgical approaches for these women. D and C alone or D and C followed by hysterectomy was the surgical approach. Majorly 82 cases (82 %) were associated with secretory endometrium on histopathology and 18 (18 %) cases were associated with the proliferative type of endometrium. Conclusion: The majority of endometrium was revealed by histopathology in the secretory phase and hysterectomy remained the commonest method of intervention.

 

 

 

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Dates

Accepted
2022-10-30

References

  • 1. Munro MG. Classification of menstrual bleeding disorders. Reviews in Endocrine and Metabolic Disorders. 2012;13(4):225-34. 2. Mencaglia L, Perino A, Hamou J. Hysteroscopy in perimenopausal and postmenopausal women with abnormal uterine bleeding. The Journal of Reproductive Medicine. 1987;32(8):577-82. 3. NICE. Clinical Guideline 44; Heavy menstrual bleeding 2007. National Institute for Health and Clinical Excellence (NICE). 4. Lasmar RB, Dias R, Barrozo PR, et al. Prevalence of hysteroscopic findings and histologic diagnoses in patients with abnormal uterine bleeding. Fertility and sterility. 2008; 89(6):1803-7. 5. Kinake M, Watane S, Deshpande S. Clinicopathological study of abnormal uterine bleeding: a two-year study at tertiary care center. International Journal of Medical Research & Health Sciences. 2021;10(6):1-8. 6. Jagdale NG, Gawandi P, Tirankar V. A study of histopathological correlation of abnormal uterine bleeding with clinical symptoms. Medpulse International Journal of Gynecology. 2020;16(2):17-22. 7. Ramachandran T, Sinha P. Subarmanium. Correlation between clinico - pathological and ultrasonographical findings. J Clin Diagn Res. 2011;5(4):737-40. 8. Nayak SR, Vaidya R, Thakur S. Geriatric problem: Abnormal uterinebleeding per vaginum after the age of 40. Journal of Obstetrics and Gynecology India. 1976;44(3):580-6. 9. Khrouf M, Terras K. Diagnosis and management of formerly called dysfunctional uterine bleeding according to PALM-COEIN FIGO classification and the new guidelines. J Obstet Gynaecol India. 2014;64 (6): 388-93. 10. Munro MG, Critchley HOD, Fraser IS. The FIGO systems for nomenclature and classification of causes of abnormal uterine bleeding in the reproductive years: who needs them? Am J Obstet Gynaecol. 2012; 207(4):259-65. 11. Madhra M, Fraser IS, Munro MG, et al. A bnormal uterine bleeding: advantages of formal classification to patients, clinicians and researchers. Acta Obstet Gynaecol Scand. 2014 ;93 (7):619-25. 12. Bahamondes L, Ali M. Recent advances in managing and understanding menstrual disorders. F 1000 Prime Rep. 2015; 7:33. 13. Gouri SRS, Lakshmi PV, Rani NG, et al. Categorization of the causes of AUB according to PALM- COEIN classification. International Journal of Scientific Study. 2016;4(2):104-7. 14. Goel P, Rathore SB. PALM-COEIN FIGO classification for diagnosis of abnormal uterine bleeding. Sch J App Med Sci. 2016;4(8A):2771-3. 15. Qureshi FU, Yusuf AW. Distribution of causes of abnormal uterine bleeding using the new FIGO classification system. J Pak Med Assoc. 2013;63: 973-75. 16. Ratnani R, Meena N. A clinicopathological analysis of causes of abnormal uterine bleeding according to PALM-COEIN classification. JMSCR. 2017;5(09):28196-200. 17. Novak ER, Jones JS, Jones HW. Novak's text book of gynecology. 8th edn. Baltimore: Lippincot William and Wilkins. 1971: 319. 18. Takreem A, Danish N, Razaq S. Incidence of endometrial hyperplasia in100 cases presenting with polymen orrhagia /menorrhagiainperimenop ausal women. J Ayub Med Coll Abbottabad. 2009; 21(2):60-3. 19. Bhattacharji SK. Dysfunctional uterine bleeding, correlation of endometrial pattern with clinical behavior. J Obstet and Gynecol India. 1964; 14:372-9. 20. Al-Rawee R., Al-Fathy D. M., & Bashir Alsabee, D. W. Delivering Integrated Health Care: Role and Importance of Multidisciplinary Team Clinic Role and Importance of Multidisciplinary Team Clinic in Nineveh Province. Journal of Medical Research and Health Sciences. 2022; 5(10): 2278–2294.