A Hospital-Based Study to Assess the Role of Serum Vitamin D Levels in Severity of Dengue Fever - A Cross Sectional Study
Authors/Creators
- 1. Assistant Professor, Department of Medicine, Nalanda Medical College and Hospital, Patna, Bihar, India
- 2. Associate Professor, Department of Medicine, Nalanda Medical College and Hospital, Patna, Bihar, India
- 3. Senior Resident, Department of Medicine, Nalanda Medical College and Hospital, Patna, Bihar, India
Description
Aim: The aim of the present study was to compare the therapeutic efficacy of autologous PRFM versus triple combination paste (zinc oxide, phenytoin, and mupirocin ointment) in non-healing ulcers. Methods: The present clinical trial was conducted in the Department of Dermatology, Patna Medical College and Hospital, Patna, Bihar, India for one year. A total of 20 patients were included in the study with the age range 20–70 years. Patients with non-healing ulcers were selected from the outpatient department of Skin and VD. Results: A total of 20 cases of non-healing ulcers of varying etiologies were treated using autologous platelet rich fibrin (PRF) at weekly intervals for maximum frequency of 6 sittings respectively. The mean age of the patients was 39.7 ± 13.02 years. Out of 20 ulcers, there were 7 (35%) venous ulcers, 3 (15%) traumatic ulcers, 6 (30%) diabetic ulcers and 4 (20%) trophic ulcers. Group A showed a mean reduction in the ulcer area by 8.26 mm2 (75.90%) which is highly significant (P-value = 0.0002). Group B showed a mean reduction in the ulcer area by 4.500 mm2 (45%) which is also significant (P-value = 0.015). Conclusion: This procedure is simple, patient-friendly, cost-effective, painless and can be performed as an outpatient procedure. We concluded that autologous platelet-rich fibrin matrix is much more effective than the triple combination paste (zinc oxide, phenytoin, and mupirocin ointment) in the treatment of non-healing ulcers.
Abstract (English)
Aim: The aim of the present study was to compare the therapeutic efficacy of autologous PRFM versus triple combination paste (zinc oxide, phenytoin, and mupirocin ointment) in non-healing ulcers. Methods: The present clinical trial was conducted in the Department of Dermatology, Patna Medical College and Hospital, Patna, Bihar, India for one year. A total of 20 patients were included in the study with the age range 20–70 years. Patients with non-healing ulcers were selected from the outpatient department of Skin and VD. Results: A total of 20 cases of non-healing ulcers of varying etiologies were treated using autologous platelet rich fibrin (PRF) at weekly intervals for maximum frequency of 6 sittings respectively. The mean age of the patients was 39.7 ± 13.02 years. Out of 20 ulcers, there were 7 (35%) venous ulcers, 3 (15%) traumatic ulcers, 6 (30%) diabetic ulcers and 4 (20%) trophic ulcers. Group A showed a mean reduction in the ulcer area by 8.26 mm2 (75.90%) which is highly significant (P-value = 0.0002). Group B showed a mean reduction in the ulcer area by 4.500 mm2 (45%) which is also significant (P-value = 0.015). Conclusion: This procedure is simple, patient-friendly, cost-effective, painless and can be performed as an outpatient procedure. We concluded that autologous platelet-rich fibrin matrix is much more effective than the triple combination paste (zinc oxide, phenytoin, and mupirocin ointment) in the treatment of non-healing ulcers.
Files
IJPCR,Vol14,Issue10,Article78.pdf
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Additional details
Dates
- Accepted
-
2022-10-03
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue10,Article78.pdf
- Development Status
- Active
References
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