Published December 31, 2022 | Version https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue12,Article85.pdf
Journal article Open

Chronic Kidney Disease and Dyslipidemias

  • 1. Junior Resident-3, Department of General Medicine, Government Medical College, Aurangabad, Maharashtra, India
  • 2. Associate Professor, Department of General Medicine, Government Medical College, Aurangabad, Maharashtra, India
  • 3. Professor & Head, Department of General Medicine, Government Medical College, Aurangabad, Maharashtra, India

Description

Introduction: Patients of chronic kidney disease (CKD), like patients of end-stage renal disease, those who were treated with dialysis, or renal transplant recipients have an increased risk for cardiovascular disease (CVD) morbidity and mortality. Dyslipidemia is commonly seen in CKD patients, CKD is an important risk factor for cardiovascular disease (CVD) development. The purpose of this study was to study of significance of dyslipidemia in patients with chronic Kidney disease because these patients have high mortality rate due cardiovascular disease or cerebrovascular disease. Materials and Methods: This study was a cross sectional, observational study done in tertiary health care hospital and teaching institute, study period was from December 2018 to December 2020. A total 60 cases were included in this study as per inclusion criteria and exclusion criteria. Results: In the present study serum samples of 60 patients were studied to know the incidence of dyslipidemia in chronic kidney disease patients, the triglycerides, cholesterol, LDL and HDL values were measured and compared as per age and sex distribution.  The p values were found to be insignificant. Conclusion: The mean values of the lipid profile showed a borderline elevation of serum triglycerides, Serum cholesterol, HDL and LDL values were within normal range. There was no statistically significant variation in the lipid profile of the patients when compared with the co-morbid conditions of diabetes mellitus and hypertension.

 

 

 

Abstract (English)

Introduction: Patients of chronic kidney disease (CKD), like patients of end-stage renal disease, those who were treated with dialysis, or renal transplant recipients have an increased risk for cardiovascular disease (CVD) morbidity and mortality. Dyslipidemia is commonly seen in CKD patients, CKD is an important risk factor for cardiovascular disease (CVD) development. The purpose of this study was to study of significance of dyslipidemia in patients with chronic Kidney disease because these patients have high mortality rate due cardiovascular disease or cerebrovascular disease. Materials and Methods: This study was a cross sectional, observational study done in tertiary health care hospital and teaching institute, study period was from December 2018 to December 2020. A total 60 cases were included in this study as per inclusion criteria and exclusion criteria. Results: In the present study serum samples of 60 patients were studied to know the incidence of dyslipidemia in chronic kidney disease patients, the triglycerides, cholesterol, LDL and HDL values were measured and compared as per age and sex distribution.  The p values were found to be insignificant. Conclusion: The mean values of the lipid profile showed a borderline elevation of serum triglycerides, Serum cholesterol, HDL and LDL values were within normal range. There was no statistically significant variation in the lipid profile of the patients when compared with the co-morbid conditions of diabetes mellitus and hypertension.

 

 

 

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Additional details

Dates

Accepted
2022-12-12

References

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