A Hospital Based Comparative Evaluation of the Diagnostic Accuracy of FNAC with Histopathology in Benign and Malignant Breast Lumps
Creators
- 1. Senior Resident, Department of Pathology, AIIMS, Patna, Bihar, India
Description
Aim: The aim of the present study was to compare the diagnostic accuracy of fine needle aspiration cytology (FNAC) and with histopathological correlation in patients with detectable breast lesions. Methods: The study was conducted in the Department of Pathology, AIIMS, Patna, Bihar, India for a period of two years. During this period, 120 fine needle aspiration were performed for various breast lumps. Out of these, 60 patients underwent surgery and form the material of the study. Results: A total of 60 patients presenting with palpable breast lumps were included in this study. The maximum number of patients attended were in 41–50 years of age group ( 18 cases, 30%), followed by 51–60 years (25%) with mean age of the patient was 46.93 years. The maximum number of benign lesions (12 in number) occurred in 31–40 years of age group and the maximum number of malignant lesions (18 in numbers) occurred in 41–50 years of age group. In FNAC, 57 cases were labelled as benign and 3 cases were malignant. Out of the 60 cases, 40 patients had fibroadenoma, 2 patients had phylloid tumor, 1 tubular adenoma, 3 fibrocystic disease of breast, 4 patients had inflammatory or breast abscess, 2 patients had gynaecomastia and in 2 cases no opinion was given. Out of the 4 malignant cases in HPE, 2 patients had a diagnosis of ductal cell carcinoma and 4 patients infiltrating ductal carcinoma. Conclusion: Fine needle aspiration cytology is a comfortable, easy, reliable, rapid and simple diagnostic test. The FNAC of breast lump should be used with” triple test” for preliminary investigation in outdoor patient department, which will further enhance the diagnostic accuracy of breast lumps.
Abstract (English)
Aim: The aim of the present study was to compare the diagnostic accuracy of fine needle aspiration cytology (FNAC) and with histopathological correlation in patients with detectable breast lesions. Methods: The study was conducted in the Department of Pathology, AIIMS, Patna, Bihar, India for a period of two years. During this period, 120 fine needle aspiration were performed for various breast lumps. Out of these, 60 patients underwent surgery and form the material of the study. Results: A total of 60 patients presenting with palpable breast lumps were included in this study. The maximum number of patients attended were in 41–50 years of age group ( 18 cases, 30%), followed by 51–60 years (25%) with mean age of the patient was 46.93 years. The maximum number of benign lesions (12 in number) occurred in 31–40 years of age group and the maximum number of malignant lesions (18 in numbers) occurred in 41–50 years of age group. In FNAC, 57 cases were labelled as benign and 3 cases were malignant. Out of the 60 cases, 40 patients had fibroadenoma, 2 patients had phylloid tumor, 1 tubular adenoma, 3 fibrocystic disease of breast, 4 patients had inflammatory or breast abscess, 2 patients had gynaecomastia and in 2 cases no opinion was given. Out of the 4 malignant cases in HPE, 2 patients had a diagnosis of ductal cell carcinoma and 4 patients infiltrating ductal carcinoma. Conclusion: Fine needle aspiration cytology is a comfortable, easy, reliable, rapid and simple diagnostic test. The FNAC of breast lump should be used with” triple test” for preliminary investigation in outdoor patient department, which will further enhance the diagnostic accuracy of breast lumps.
Files
IJPCR,Vol15,Issue2,Article159.pdf
Files
(271.2 kB)
Name | Size | Download all |
---|---|---|
md5:6c79fbb49de15aabc155891f9fd051c4
|
271.2 kB | Preview Download |
Additional details
Dates
- Accepted
-
2023-02-04
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue2,Article159.pdf
- Development Status
- Active
References
- 1. Ahmed I, Nazir R, Chaudhary M, Kundi S. Triple assessment of breast lump. J Coll Phys Surg Pak. 2007; 17(9):535–8. 2. Hussain MT. Comparison of fine needle aspiration cytology with excision biopsy of breast lump. J Coll Phys Surg Pak. 2005;15(4):211–4 3. Yong WS, Chia KH, Poh WT and Wong CY. A comparison of trucut biopsy with fine needle aspiration cytology in the diagnosis of breast cancer. Singapore Med J. 1999; 40(9): 587-589. 4. Rahman MZ, Islam S. Fine needle aspiration cytology of palpable breast lump: A study of 1778 cases. Surgery S. 2013; 12:2161-1076. 5. Obaseki DE, Olu-Edo AN, Ogunbiyi JO. Diagnostic accuracy of fine needle aspiration cytology of palpable breast masses in Benin City, Nigeria. West Afr J Med. 2010; 29(4):259-262. 6. Ukah CO, Oluwasola OO. The clinical effectiveness of fine needle aspiration biopsy in patients with palpable breast lesions seen at the University College Hospital, Ibadan, Nigeria: A 10-year retrospective study. J Cytol. 2011; 28(3): 111–113. 7. Jindal U, Singh K, Kochhar A. Fine Needle Aspiration Cytology of Breast Lumps with Histopathological Correlation: A Four Year and eightmonth study from rural India. Internet J Pathol. 2012; 13(3). 8. Das DK. Fine Needle aspiration Cytology: Its origin, development andpresent status with special reference to a developing country, India. Diagn Cytopathol. 2003; 28(6): 345-351. 9. Fraznen S, Zajicek J. Aspiration Biopsy in Diagnosis of Palpable Lesions of the Breast: Critical review of 3 479 consecutive biopsies. Acta radiologica: therapy, physics, biology. 1968 Jan 1;7(4):241-62. 10. Berner A, Torill Sauer T. Fine-needle Aspiration Cytology of the Breast. Ultrastruct Pathol. 2011; 35(4): 162– 167. 11. Tham TM, Rangaswamy Iyengar K, Taib NA, Yip CH. Fine needle aspiration biopsy, core needle biopsy or excision biopsy to diagnose breast cancer-which is the ideal method? Asian Pacific Journal of Cancer Prevention. 2009;10(1):155-8. 12. Pinto R, Singh K. A statistical analysis of fine needle aspiration biopsies in palpable benign (neoplastic and nonneoplastic) breast lesions. J Cytol. 2004;21(2):64–7. 13. Tanikella R, Prabhala S, Tallam US. Histopathological and cytological correlation of tumors of breast. Med J Dr DY Patil Univ. 2014;7(3):326–11. 14. Ishita P, Singh PK. Cytomorphologic study of palpable breast lesions and histopathologic correlation. J Cytol. 2003; 20:129-32. 15. Chaudary MA, Fentiman IS. Followup of patients with aspirated breast cysts is necessary. Arch Surg. 1989; 124(2):253–5. 16. Hughes JE, Royle G, Buchanan R, Taylor I. Depression and social stress among patients with benign breast disease. J Br Surg. 1986;73(12):997–9. 17. Ellman R, Angeli N, Christians A, Moss S, Chamberlain J, Maguire P. Psychiatric morbidity associated with screening for breast cancer. Br J Cancer. 1989;60(5):781–4. 18. Hays P. Evidence Basis for Pharmacogenetic Testing in Psychiatry. Journal of Medical Research and Health Sciences. 2022; 5(3): 1838–1859.