Published February 28, 2023 | Version https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue2,Article110.pdf
Journal article Open

A Comparative Study to Detect Tuberculosis in Pregnant Women with and Without Diabetes

  • 1. Associate Professor, Department of Pathology, Bhaarath Medical College and Hospital, Agaram Main Road, Selaiyur, Chennai
  • 2. Assistant Professor, Department of Obstetrics and Gynaecology, GSL Medical College, Rajahmundry
  • 3. Assistant Professor, Department of Pulmonary Medicine, Government Medical College, Srikakulam
  • 4. Assistant Professor, Department of Biochemistry, Osmania Medical College, Hyderabad

Description

Introduction: Diabetes mellitus (DM) was reported to be the major issue to control the spread of tuberculosis (TB). With these, a study was conducted to find the utility of FS in the diagnosis of pulmonary tuberculosis (PT) among the pregnant women. Methods: It was a prospective study, conducted in GSL Medical College. In this research sputum samples which were submitted to institutional Microscopy centre were considered. In this research, pregnant women with DM, symptoms of cough for > 2 weeks were considered. Non cooperative members and non DM were not considered in this research. Then the participants were provided with sterile, plastic containers and they were asked to collect the sample. Collection of sputum sample, smear preparation as well ZN and fluorescent staining (FS) were carried as per the protocol. The data were analysed using SPSS version 21. Chi square test was used to find the statistical analysis. P <0.05 was considered to be statistically significant. Results: Total 106 participants were included in this study. Maximum (32.8%; 34) in 21 – 25 years group; the mean age of the study members was 31.3 years. Total 8 (100%) PT cases were detected using FS. By using ZN staining 5 (4.5%) PT cases were detected; statically there was no significant difference. Maximum PT cases were detected in in 21 – 25 (5; 62.5%) years group. Conclusion: FS technique has better diagnostic yield to detect pulmonary tuberculosis among the pregnant women with DM. But small sample and short duration of the study are the limitations of the research.

 

 

 

Abstract (English)

Introduction: Diabetes mellitus (DM) was reported to be the major issue to control the spread of tuberculosis (TB). With these, a study was conducted to find the utility of FS in the diagnosis of pulmonary tuberculosis (PT) among the pregnant women. Methods: It was a prospective study, conducted in GSL Medical College. In this research sputum samples which were submitted to institutional Microscopy centre were considered. In this research, pregnant women with DM, symptoms of cough for > 2 weeks were considered. Non cooperative members and non DM were not considered in this research. Then the participants were provided with sterile, plastic containers and they were asked to collect the sample. Collection of sputum sample, smear preparation as well ZN and fluorescent staining (FS) were carried as per the protocol. The data were analysed using SPSS version 21. Chi square test was used to find the statistical analysis. P <0.05 was considered to be statistically significant. Results: Total 106 participants were included in this study. Maximum (32.8%; 34) in 21 – 25 years group; the mean age of the study members was 31.3 years. Total 8 (100%) PT cases were detected using FS. By using ZN staining 5 (4.5%) PT cases were detected; statically there was no significant difference. Maximum PT cases were detected in in 21 – 25 (5; 62.5%) years group. Conclusion: FS technique has better diagnostic yield to detect pulmonary tuberculosis among the pregnant women with DM. But small sample and short duration of the study are the limitations of the research.

 

 

 

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Dates

Accepted
2023-02-28

References

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