Cardiorenal Syndrome in Heart Failure Patients: A Descriptive and Predictive Study
Authors/Creators
- 1. Junior Specialist (M.D.), Department of General Medicine, General Hospital, Alwar, Rajasthan, India
- 2. Medical officer (M.D.), Department of General Medicine, General Hospital, Alwar, Rajasthan, India
- 3. Senior Specialist (M.D.), Department of General Medicine, General Hospital, Alwar, Rajasthan, India
Description
Aim & Objectives: This study aims to evaluate the prevalence, contributing causes, and consequences of Cardiorenal syndrome (CRS) in patients with heart failure (HF) admitted to medical wards of a tertiary care hospital. Material & Methods: The research employed a cross-sectional design. During a 15-month period, patients who met the specific requirements and were at least 18 years old were recruited individually. In addition to the essential first blood tests, such as blood profile, CBC, urine analysis, eGFR, ECG, echocardiography, and renal USG, a comprehensive medical history and physical examination were conducted. The urine protein creatinine ratio was evaluated in individuals with proteinuria. At the initial presentation, serum creatinine, urea, and electrolyte levels were assessed. Subsequently, over the course of heart failure therapy, identical measurements were repeated. The precise description and categorization of heart failure and CRS were achieved utilising acceptable criteria. Statistical analysis conducted with the SPSS programme. Results: Out of the 100 patients examined, the average age was 50.639±13.401, with 62 being men and 38 being females. Out of the total, 53 individuals had cardiorenal impairment, whereas 47 individuals were exclusively in the heart failure patient group. The CRS group, including 86.8% of the participants, consists of individuals aged 40 and above (p=0.0401) who have a high prevalence of diabetes. In contrast, the non-CRS group, accounting for 76% of the participants, does not smoke. The majority of individuals impacted suffer from type 1 CRS, and 72.5% of CRS cases are classified as moderate CRS. High levels of serum urea (>120 mg/dl) and serum creatinine (>1.91 mg/dl) can be used to predict mortality. Individuals diagnosed with CRS exhibited significantly greater mortality rates compared to those who did not have the illness. Conclusion: Patients with heart failure exhibited markedly elevated rates of CRS. Individuals who were beyond the age of 40 and classified as NYHA class 4 were found to be independent predictors of CRS. Individuals with chronic rhinosinusitis (CRS) had significantly prolonged hospital stays compared to individuals without CRS. Within a hospital setting, the death rate for individuals with CRS is significantly elevated. Serum urea and creatinine serve as crucial indicators of mortality.
Abstract (English)
Aim & Objectives: This study aims to evaluate the prevalence, contributing causes, and consequences of Cardiorenal syndrome (CRS) in patients with heart failure (HF) admitted to medical wards of a tertiary care hospital. Material & Methods: The research employed a cross-sectional design. During a 15-month period, patients who met the specific requirements and were at least 18 years old were recruited individually. In addition to the essential first blood tests, such as blood profile, CBC, urine analysis, eGFR, ECG, echocardiography, and renal USG, a comprehensive medical history and physical examination were conducted. The urine protein creatinine ratio was evaluated in individuals with proteinuria. At the initial presentation, serum creatinine, urea, and electrolyte levels were assessed. Subsequently, over the course of heart failure therapy, identical measurements were repeated. The precise description and categorization of heart failure and CRS were achieved utilising acceptable criteria. Statistical analysis conducted with the SPSS programme. Results: Out of the 100 patients examined, the average age was 50.639±13.401, with 62 being men and 38 being females. Out of the total, 53 individuals had cardiorenal impairment, whereas 47 individuals were exclusively in the heart failure patient group. The CRS group, including 86.8% of the participants, consists of individuals aged 40 and above (p=0.0401) who have a high prevalence of diabetes. In contrast, the non-CRS group, accounting for 76% of the participants, does not smoke. The majority of individuals impacted suffer from type 1 CRS, and 72.5% of CRS cases are classified as moderate CRS. High levels of serum urea (>120 mg/dl) and serum creatinine (>1.91 mg/dl) can be used to predict mortality. Individuals diagnosed with CRS exhibited significantly greater mortality rates compared to those who did not have the illness. Conclusion: Patients with heart failure exhibited markedly elevated rates of CRS. Individuals who were beyond the age of 40 and classified as NYHA class 4 were found to be independent predictors of CRS. Individuals with chronic rhinosinusitis (CRS) had significantly prolonged hospital stays compared to individuals without CRS. Within a hospital setting, the death rate for individuals with CRS is significantly elevated. Serum urea and creatinine serve as crucial indicators of mortality.
Files
IJPCR,Vol16,Issue7,Article101.pdf
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Additional details
Dates
- Accepted
-
2024-06-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue7,Article101.pdf
- Development Status
- Active
References
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