A Retrospective, Randomized, Double-Blind Study Was Done to Compare between Intrathecal Dexmedetomidine (5mcg) and Intrathecal Meperidine (0.2mg/Kg) for Decreasing the Incidence and Intensity of Shivering after Spinal Anesthesia for Lower Abdominal Operations.
Authors/Creators
- 1. Senior Resident, Department of Anesthesia, Vardhman Institute of Medical Science, Pawapuri, Nalanda, Bihar, India
- 2. PG, Department of Pathology, Darbhanga Medical College and Hospital, Darbhanga, Bihar, India
- 3. Junior Resident, Department of Anesthesiology and Critical care, Patna Medical College and Hospital, Patna, Bihar, India
- 4. Assistant Professor and HOD, Department of Anesthesia, Vardhman Institute of Medical Science, Pawapuri, Nalanda, Bihar, India
Description
Abstract
Aim: to compare between intrathecal dexmedetomidine (5mcg) and intrathecal meperidine (0.2mg/kg) for
decreasing the incidence and intensity of shivering after spinal anesthesia for lower abdominal operations.
Methods: The present study was conducted in the Department of Anesthesia, Vardhman Institute of Medical
Science, Pawapuri, Nalanda, Bihar, India from jan 2017 to December 2017, and ninety patients scheduled for
lower abdominal operations under spinal anesthesia were randomly allocated to three groups. Spinal anesthesia
consisted of 12.5 mg hyperbaric bupivacaine 0.5% in addition to dexmedetomidine (5mcg) (group D) or
meperidine (0.2 mg/kg) (group M) or, normal saline (group S). Different parameters, including sublingual
temperature, sensory block, motor block, incidence and intensity of shivering, blood pressure, heart rate, pruritus,
nausea, and vomiting was performed at 10-minute intervals.
Results: Hypothermia was recorded in 17 patients in group D, 16 patients in group M and 18 patients in group S,
while shivering developed in 6 patients in group D, 7 patients in group M and 8 patients in group S, however,
pruritus, nausea and vomiting was more common in the meperidine group compared to the other two groups.
Conclusion: To conclude, intrathecal dexmedetomidine and meperidine lowered the incidence of shivering and
increased duration of sensory and motor block during lower abdominal operations. Intrathecal meperidine caused
more pruritus, nausea and vomiting than intrathecal dexmedetomidine.
Abstract (English)
Abstract
Aim: to compare between intrathecal dexmedetomidine (5mcg) and intrathecal meperidine (0.2mg/kg) for
decreasing the incidence and intensity of shivering after spinal anesthesia for lower abdominal operations.
Methods: The present study was conducted in the Department of Anesthesia, Vardhman Institute of Medical
Science, Pawapuri, Nalanda, Bihar, India from jan 2017 to December 2017, and ninety patients scheduled for
lower abdominal operations under spinal anesthesia were randomly allocated to three groups. Spinal anesthesia
consisted of 12.5 mg hyperbaric bupivacaine 0.5% in addition to dexmedetomidine (5mcg) (group D) or
meperidine (0.2 mg/kg) (group M) or, normal saline (group S). Different parameters, including sublingual
temperature, sensory block, motor block, incidence and intensity of shivering, blood pressure, heart rate, pruritus,
nausea, and vomiting was performed at 10-minute intervals.
Results: Hypothermia was recorded in 17 patients in group D, 16 patients in group M and 18 patients in group S,
while shivering developed in 6 patients in group D, 7 patients in group M and 8 patients in group S, however,
pruritus, nausea and vomiting was more common in the meperidine group compared to the other two groups.
Conclusion: To conclude, intrathecal dexmedetomidine and meperidine lowered the incidence of shivering and
increased duration of sensory and motor block during lower abdominal operations. Intrathecal meperidine caused
more pruritus, nausea and vomiting than intrathecal dexmedetomidine.
Files
IJCPR,Vol16,Issue4,Article126.pdf
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Additional details
Dates
- Accepted
-
2024-04-29