A Retrospective Assessment of Common Bacteria Associated with UTI Cases and Their Antibiotic Susceptibility Pattern

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Abstract (English)

Abstract
Aim: The aim of the present study was to investigate the common bacteria associated with UTI cases and their
antibiotic susceptibility pattern.
Methods: A retrospective study was done for one year( January 2021 to December 2021) in Department of
Pharmacology, ANMMCH, Gaya, Bihar, India. The study included all in-patients of either gender above 18 years
of age with a diagnosis of UTI. Data was collected from the patient’s case record files, which were retrieved from
the medical records department of our hospital.
Results: Out of 120 significant isolates, gram-negative organisms accounted for 81%. Fungal isolates were seen
only in 2% of cases. E.coli was the most predominant uropathies isolated followed by Klebsiella spp, Enterococcus
faecalis and Acinetobacter spp. Other uropathies included MRSA bacteria, Staphylococcus aureus, Candida spp,
Citrobacter Freunde, Pseudomonas spp and Streptococcus spp. E.coli, showed considerable resistance to
ampicillin, ceftriaxone, Co-Trimoxazole and fluoroquinolones. Low level of resistance was observed with
Nitrofurantoin, piperacillin+ tazobactam and Ticarcillin. Klebsiella spp, the second most common uropathies
showed high level of resistance with ampicillin, cephalexin, cefuroxime, ceftriaxone and Nitrofurantoin.
Conclusion: Most of the identified bacteria were resistant to several of the popular antibiotics used in clinical
settings. Consequently, it is vital to prescribe antibiotics rationally both before and after culture reports. Pattern
needs to be studied further and the outcome should be communicated to the prescribing physicians in that area.