Serum Lactate Dehydrogenase: A Biochemical Marker for the Prediction of Adverse Outcome in Pre-Eclampsia
Authors/Creators
- 1. Junior Resident, Department of Obstetrics and Gynaecology, BVDU MCH, Sangli
- 2. Professor& HOD, Department of Obstetrics and Gynaecology, BVDUMCH, Sangli
- 3. Junior Resident, Department of Obstetrics and Gynaecology, BVDUMCH, Sangli
Description
Aims & Objectives: To find out the role of serum LDH levels in prediction of adverse outcome of pre- eclampsia” Objectives: 1) To estimate the level of serum LDH in preeclampsia. 2) To study the correlation of LDH level and severity of the disease.3) To study the correlation of LDH level and occurrence of complications. 4) To identify the better severity indicator in maternal and perinatal outcomes. Materials & Methods: A study was conducted over a period of 6 months in the department of Obstetrics and Gynaecology, Bharati Vidyapeeth medical college and hospital, Sangli. Women with pre-eclampsia were studied who satisfied the inclusion and exclusion criteria of the study. Demographic, hemodynamic, laboratory data were compared among 2 groups. The symptoms and complications of severe pre-eclampsia along with the fetal outcome were analysed according to serum LDH levels. Results: Severely pre eclamptic women patients were significantly younger, with low gravidity and parity. Higher LDH levels have significant correlation with high BP. The symptoms and complications of pre-eclampsia along with perinatal mortality were increased significantly in pt with LDH>800IU/L compared with those who had lower levels. Conclusion: Serum LDH is useful biomarker and can be considered as a supportive prognostic tool that reflects the severity of disease and complications of pre-eclampsia. Identification of high-risk patient with increased level of LDH mandate their close monitoring and correct management may prevent these complications.
Abstract (English)
Aims & Objectives: To find out the role of serum LDH levels in prediction of adverse outcome of pre- eclampsia” Objectives: 1) To estimate the level of serum LDH in preeclampsia. 2) To study the correlation of LDH level and severity of the disease.3) To study the correlation of LDH level and occurrence of complications. 4) To identify the better severity indicator in maternal and perinatal outcomes. Materials & Methods: A study was conducted over a period of 6 months in the department of Obstetrics and Gynaecology, Bharati Vidyapeeth medical college and hospital, Sangli. Women with pre-eclampsia were studied who satisfied the inclusion and exclusion criteria of the study. Demographic, hemodynamic, laboratory data were compared among 2 groups. The symptoms and complications of severe pre-eclampsia along with the fetal outcome were analysed according to serum LDH levels. Results: Severely pre eclamptic women patients were significantly younger, with low gravidity and parity. Higher LDH levels have significant correlation with high BP. The symptoms and complications of pre-eclampsia along with perinatal mortality were increased significantly in pt with LDH>800IU/L compared with those who had lower levels. Conclusion: Serum LDH is useful biomarker and can be considered as a supportive prognostic tool that reflects the severity of disease and complications of pre-eclampsia. Identification of high-risk patient with increased level of LDH mandate their close monitoring and correct management may prevent these complications.
Files
IJPCR,Vol15,Issue3,Article197.pdf
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Additional details
Dates
- Accepted
-
2023-03-25
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue3,Article197.pdf
- Development Status
- Active
References
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