Published April 30, 2024 | Version v1
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An Analytical Study Evaluating Iron Deficiency Anemia and its Association with Acute Bronchiolitis in Children Admitted at Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar.

  • 1. Senior Resident, Department of Pediatrics, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India
  • 2. Associate professor and HOD, Department of Pediatrics, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India

Description

Aim: The aim of the present study was to evaluate whether iron deficiency anemia is associated with acute
bronchiolitis in children.
Material & Methods: This Analytical study was carried out in the Department of Paediatrics, at ANMMCH,
Gaya, Bihar for the period between March 2022 to February 2023 ( one-year) after obtaining ethical approval to
explore the association between iron deficiency anemia and bronchiolitis. For this purpose, a total number of 100
patients were enrolled in the study and among them, 50 children with bronchiolitis were considered as cases, and
50 healthy children without bronchiolitis were considered as control, who were matched with age.
Results: Majority of the patients were in the age group between 13-18 months. The mean age was found
13.077±5.725 months in cases and 15.115±7.953 months in controls. The mean age difference was not significant
between the two groups (p>0.05). Male participants (32, 64%) were the predominant group in the study and female
participants (18, 36%). Exclusive breastfeeding was found in 15 cases and 32 controls respectively. The
differences were statistically significant (p<0.05) between the two groups in the chi-square test. Overcrowding
was found in 38 cases and 30 controls respectively. There was a significant difference in Hb (gm/dl) between
cases and controls followed by MCV (fl) between cases and controls. The MCH (pg) level was statistically and
significantly lower in cases compared to controls; followed by MCHC (g/dl) which was statistically and
significantly lower in cases compared to controls. S. Iron (µg/dl) was statistically and significantly lower in
cases compared to controls. Transferrin Saturation (%) was statistically and significantly lower in cases compared
to controls. RDW-CV (%) was statistically and significantly higher in cases compared to controls. Among the 100
study subjects 40 cases had anemia, followed by 30 controls had anemia. Their difference was statistically
significant between the two groups (p<0.05).
Conclusion: Iron deficiency anemia has a significant association with bronchiolitis. A larger and more extensive
study was recommended.

Abstract (English)

Aim: The aim of the present study was to evaluate whether iron deficiency anemia is associated with acute
bronchiolitis in children.
Material & Methods: This Analytical study was carried out in the Department of Paediatrics, at ANMMCH,
Gaya, Bihar for the period between March 2022 to February 2023 ( one-year) after obtaining ethical approval to
explore the association between iron deficiency anemia and bronchiolitis. For this purpose, a total number of 100
patients were enrolled in the study and among them, 50 children with bronchiolitis were considered as cases, and
50 healthy children without bronchiolitis were considered as control, who were matched with age.
Results: Majority of the patients were in the age group between 13-18 months. The mean age was found
13.077±5.725 months in cases and 15.115±7.953 months in controls. The mean age difference was not significant
between the two groups (p>0.05). Male participants (32, 64%) were the predominant group in the study and female
participants (18, 36%). Exclusive breastfeeding was found in 15 cases and 32 controls respectively. The
differences were statistically significant (p<0.05) between the two groups in the chi-square test. Overcrowding
was found in 38 cases and 30 controls respectively. There was a significant difference in Hb (gm/dl) between
cases and controls followed by MCV (fl) between cases and controls. The MCH (pg) level was statistically and
significantly lower in cases compared to controls; followed by MCHC (g/dl) which was statistically and
significantly lower in cases compared to controls. S. Iron (µg/dl) was statistically and significantly lower in
cases compared to controls. Transferrin Saturation (%) was statistically and significantly lower in cases compared
to controls. RDW-CV (%) was statistically and significantly higher in cases compared to controls. Among the 100
study subjects 40 cases had anemia, followed by 30 controls had anemia. Their difference was statistically
significant between the two groups (p<0.05).
Conclusion: Iron deficiency anemia has a significant association with bronchiolitis. A larger and more extensive
study was recommended.

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Dates

Accepted
2024-04-25