Psychiatric Symptoms in Primary Fibromyalgia and Fibromyalgia Secondary to Rheumatoid Arthritis: A Comparative Study
Creators
- 1. Associate Professor, Department of Psychiatry, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India
- 2. Assistant Professor, Department of Medicine, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India
- 3. Assistant Professor, Department of Orthopaedics, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India
- 4. PGMO SNCU/PICU, KushaBhau Thakrey District Hospital, Shahdol, Madhya Pradesh, India
- 5. Associate Professor, Department of Medicine, Birsa Munda Medical College, Shahdol, Madhya Pradesh, India
Description
Introduction: Fibromyalgia (FM) is a common occurrence among patients diagnosed with rheumatoid arthritis
(RA). Our study aimed to assess the variations in psychiatric comorbidities and life challenges between
individuals with Rheumatoid arthritis plus FM (secondary fibromyalgia [SFM]) and those with primary FM
(PFM).
Materials and Methods: We recruited 45 patients with PFM and 53 with SFM for the study. This crosssectional, observational study involved structured interviews with patients diagnosed with PFM and SFM to
determine lifetime occurrences of major depression (MDD), panic disorder (PD), and post-traumatic stress
disorder (PTSD). Additionally, participants were evaluated for childhood/adulthood adversities and the severity
of FM-related symptoms.
Results: Univariate analysis revealed significantly higher lifetime rates of MDD in PFM compared to SFM, as
well as higher rates of PD, with no notable difference in PTSD rates. Furthermore, rates of sexual abuse and
physical neglect were notably higher in PFM patients than in SFM patients. Life events occurring before the
onset of FM differed between the PFM and SFM groups. In the logistic regression model, lifetime PD and
physical neglect emerged as independent risk factors for PFM.
Conclusion: These findings indicate that PFM and SFM exhibit differences in psychiatric comorbidities and
environmental adversities, suggesting that a common pathogenesis may manifest through distinct pathways.
Abstract (English)
Introduction: Fibromyalgia (FM) is a common occurrence among patients diagnosed with rheumatoid arthritis
(RA). Our study aimed to assess the variations in psychiatric comorbidities and life challenges between
individuals with Rheumatoid arthritis plus FM (secondary fibromyalgia [SFM]) and those with primary FM
(PFM).
Materials and Methods: We recruited 45 patients with PFM and 53 with SFM for the study. This crosssectional, observational study involved structured interviews with patients diagnosed with PFM and SFM to
determine lifetime occurrences of major depression (MDD), panic disorder (PD), and post-traumatic stress
disorder (PTSD). Additionally, participants were evaluated for childhood/adulthood adversities and the severity
of FM-related symptoms.
Results: Univariate analysis revealed significantly higher lifetime rates of MDD in PFM compared to SFM, as
well as higher rates of PD, with no notable difference in PTSD rates. Furthermore, rates of sexual abuse and
physical neglect were notably higher in PFM patients than in SFM patients. Life events occurring before the
onset of FM differed between the PFM and SFM groups. In the logistic regression model, lifetime PD and
physical neglect emerged as independent risk factors for PFM.
Conclusion: These findings indicate that PFM and SFM exhibit differences in psychiatric comorbidities and
environmental adversities, suggesting that a common pathogenesis may manifest through distinct pathways.
Files
IJCPR,Vol16,Issue4,Article2.pdf
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Additional details
Dates
- Accepted
-
2024-04-05