Quantitative C-reactive Protein Levels in Children with Bacterial and Other Meningitis in Cerebrospinal Fluid at Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar
Authors/Creators
- 1. Senior Resident, Department of Pediatrics, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar
- 2. Associate Professor and Head of Department, Department of Pediatrics, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar
Description
Background: In both industrialised and developing nations, bacterial meningitis is a substantial cause of morbidity and mortality in children. Individuals with suspected bacterial meningitis require immediate medical attention, however there is a substantial risk of poor outcome due to delayed and inadequate diagnosis. It is possible to enhance the prognosis of an illness with an early and accurate diagnosis of the ailment. Methods: From September 2021 to August 2022, the current study was carried out in the pediatrics department of Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar. To confirm the diagnosis, a total of 242 children who were admitted during the research period and had a clinical suspicion of meningitis underwent clinical, biochemical, cytological, and bacterial testing. Also, a quantitative amount of CSF was sent for C-reactive protein measurement using an immuno-turbidimetric latex agglutination test. Results: Only 20 of the 242 meningitis cases brought to the hospital had a positive culture. The quantitative amount of CSF CRP differed significantly between bacterial and non-bacterial meningitis. Conclusion: A useful test to distinguish pyogenic meningitis from tubercular meningitis, viral meningoencephalitis, and other non-meningitis CNS illnesses is the quantitative quantification of CRP in CSF by immunoturbidimetry. It is a simple, quick, accurate, and quick diagnostic test for prompt treatment action. The determination of CRP in CSF also influences the selection of the right antibiotic and the course of treatment.
Abstract (English)
Background: In both industrialised and developing nations, bacterial meningitis is a substantial cause of morbidity and mortality in children. Individuals with suspected bacterial meningitis require immediate medical attention, however there is a substantial risk of poor outcome due to delayed and inadequate diagnosis. It is possible to enhance the prognosis of an illness with an early and accurate diagnosis of the ailment. Methods: From September 2021 to August 2022, the current study was carried out in the pediatrics department of Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar. To confirm the diagnosis, a total of 242 children who were admitted during the research period and had a clinical suspicion of meningitis underwent clinical, biochemical, cytological, and bacterial testing. Also, a quantitative amount of CSF was sent for C-reactive protein measurement using an immuno-turbidimetric latex agglutination test. Results: Only 20 of the 242 meningitis cases brought to the hospital had a positive culture. The quantitative amount of CSF CRP differed significantly between bacterial and non-bacterial meningitis. Conclusion: A useful test to distinguish pyogenic meningitis from tubercular meningitis, viral meningoencephalitis, and other non-meningitis CNS illnesses is the quantitative quantification of CRP in CSF by immunoturbidimetry. It is a simple, quick, accurate, and quick diagnostic test for prompt treatment action. The determination of CRP in CSF also influences the selection of the right antibiotic and the course of treatment.
Files
IJPCR,Vol15,Issue3,Article138.pdf
Files
(362.7 kB)
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Additional details
Dates
- Accepted
-
2023-03-10
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue3,Article138.pdf
- Development Status
- Active
References
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