Role of Platelet Rich Plasma in Treatment of Chronic Achilles Tendinopathy
Authors/Creators
- 1. Assistant Professor, Department of Orthopaedics, G.S.V.M. Medical Collage, Kanpur
- 2. Associate Professor, Department of Obs & Gynae, Saraswati Medical Collage, Unnao
- 3. Senior Resident, Department of Anesthesia, Dr. B.S. Kushwaha Medical Collage, Kanpur
- 4. Junior Resident, RVRS Medical Collage & Mahatma Gandhi Hospital, Bhilwara, Rajasthan
Description
Introduction: It is thought that Achilles tendopathy is related to sports activities, but it is more often found in people who do not involved in sports. The biggest cause is the excessive overburdening of the tendon. At present most of the systematic review and metanalysis shows that the role of PRP in tendinopathy is insignificant. Aims and Objectives: This study focuses on Leucocyte-rich platelet rich plasma for treatment of chronic achilles tendinopathy in terms of patient reported VAS score, VISA-A Score. This work also measures tendon thickness and intratendinous vascularity by USG & Doppler study. Methodology and Results: This was a Prospective longitudinal Study/case series. Patients were injected with leucocyte rich platelet rich plasma in Achilles tendon and evaluated on 6, 12, 18 weeks postinjection. In our result VISA-A score shows improvement in initial 6 weeks then slight rise upto 18 weeks with p value of <0.001. VAS score shows initial sudden decline upto 6 week then gradual decline in score with p value of <0.001. Tendon thickness decreased in significant number of patients (80.64% patients) at 18 weeks with p value <0.001. Sudden decrease in tendon vascularity (80.64% of patients) was seen at 12 weeks (p<0.001). Conclusion: At present ongoing work in form of case series, case reports and some randomized control trials shows benificial role of PRP in Achilles tendinopathy in terms of functional / radiological / histopathological outcome indicating that further research required in field of dose and frequency of PRP administration, standardization of PRP prepration, role of adding other biologics, long term radiological / histological follow up combined with functional outcome.
Abstract (English)
Introduction: It is thought that Achilles tendopathy is related to sports activities, but it is more often found in people who do not involved in sports. The biggest cause is the excessive overburdening of the tendon. At present most of the systematic review and metanalysis shows that the role of PRP in tendinopathy is insignificant. Aims and Objectives: This study focuses on Leucocyte-rich platelet rich plasma for treatment of chronic achilles tendinopathy in terms of patient reported VAS score, VISA-A Score. This work also measures tendon thickness and intratendinous vascularity by USG & Doppler study. Methodology and Results: This was a Prospective longitudinal Study/case series. Patients were injected with leucocyte rich platelet rich plasma in Achilles tendon and evaluated on 6, 12, 18 weeks postinjection. In our result VISA-A score shows improvement in initial 6 weeks then slight rise upto 18 weeks with p value of <0.001. VAS score shows initial sudden decline upto 6 week then gradual decline in score with p value of <0.001. Tendon thickness decreased in significant number of patients (80.64% patients) at 18 weeks with p value <0.001. Sudden decrease in tendon vascularity (80.64% of patients) was seen at 12 weeks (p<0.001). Conclusion: At present ongoing work in form of case series, case reports and some randomized control trials shows benificial role of PRP in Achilles tendinopathy in terms of functional / radiological / histopathological outcome indicating that further research required in field of dose and frequency of PRP administration, standardization of PRP prepration, role of adding other biologics, long term radiological / histological follow up combined with functional outcome.
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IJPCR,Vol16,Issue6,Article407.pdf
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Additional details
Dates
- Accepted
-
2024-05-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue6,Article407.pdf
- Development Status
- Active
References
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