Published June 30, 2024 | Version v1
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A Prospective Observational Study to Assess the Clinical Spectrum and Outcome in Children with Nephrotic Syndrome

  • 1. Senior Resident, Department of Paediatrics, Jawaharlal Nehru Medical College and Hospital, Bhagalpur, Bihar India
  • 2. PG-Student, Department of Paediatrics Jawaharlal Nehru Medical College and Hospital, Bhagalpur, Bihar India
  • 3. Assistant Professor, Department of Paediatrics, Jawaharlal Nehru Medical College and Hospital, Bhagalpur, Bihar India

Description

Abstract
Aim: The aim of the present study was to assess the clinical spectrum and outcome in children with nephrotic
syndrome.
Methods: This was a prospective observational study conducted at pediatric department. 100 children who were
diagnosed with nephrotic syndrome at JLNMCH in whom steroid treatment was not started yet were included for
study purpose. Patients with first attack and relapse both were included in this study.
Results: 70% were male and 30% were females. In the present study, 100% had swelling followed by 88% had
puffiness. 100% had pitting edema and 80% had ascites. The hemoglobin, serum albumin, serum creatinine was
10.5±1.46, 1.7±0.43 and 0.62±0.18 respectively. 34% had complete remission and 15% had relapse.
Conclusion: In our study clinical and laboratory findings were in similarity with usual nephrotic syndrome in
children. There was no any significant difference in pattern of nephrotic syndrome and response to treatment from
other studies.

Abstract (English)

Abstract
Aim: The aim of the present study was to assess the clinical spectrum and outcome in children with nephrotic
syndrome.
Methods: This was a prospective observational study conducted at pediatric department. 100 children who were
diagnosed with nephrotic syndrome at JLNMCH in whom steroid treatment was not started yet were included for
study purpose. Patients with first attack and relapse both were included in this study.
Results: 70% were male and 30% were females. In the present study, 100% had swelling followed by 88% had
puffiness. 100% had pitting edema and 80% had ascites. The hemoglobin, serum albumin, serum creatinine was
10.5±1.46, 1.7±0.43 and 0.62±0.18 respectively. 34% had complete remission and 15% had relapse.
Conclusion: In our study clinical and laboratory findings were in similarity with usual nephrotic syndrome in
children. There was no any significant difference in pattern of nephrotic syndrome and response to treatment from
other studies.

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Additional details

Dates

Accepted
2024-04-29