Published July 12, 2024 | Version v1
Dataset Open

Increased spatial coupling of integrin and collagen IV in the immunoresistant clear-cell renal-cell carcinoma tumor microenvironment - Nanostring CosMx SMI Data

  • 1. ROR icon Moffitt Cancer Center

Description

Data export from Nanostring CosMx SMI, directly from Nanostring, in Seurat Object format for use in R. Clear cell renal cell carcinoma and papillary renal cell carcinoma were profiled before and after exposure to immunotherapy, with and without sarcomatoid features in clear cell tumors. Each tumor had a field of view in the stromal compartment and field of view in the tumor compartment.

For appropriate clinical information associated with this study, please contact Dr. Brandon Manley.

Files

Files (544.5 MB)

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Additional details

Software

Repository URL
https://github.com/FridleyLab/ccRCC_CosMx_SMI_2023
Programming language
R

References

  • Soupir, A. C. et al. Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironment. bioRxiv, 2023.2011.2016.567457 (2023). https://doi.org:10.1101/2023.11.16.567457