The Role of Small Intestinal Microbiota in Human Health and Disease: Current Understanding and Future Perspectives
Authors/Creators
- 1. MBBS, MGM Medical College and Hospital, Aurangabad, Maharashtra
- 2. Associate Professor, Department of Anaesthesiology, R.D.J.M Medical College and Hospital, Muzaffarpur, Bihar
Description
The small intestine microbiota is becoming recognized as performing an important role in human health and illness. This review article investigates the composition and function of the small intestine microbiota, focusing on its role in digestion, nutritional absorption, immunological regulation, and pathogen protection. We investigated the link between microbial dysbiosis and a variety of gastrointestinal, metabolic, immune-mediated, and cognitive conditions. Therapeutic approaches such as probiotics, prebiotics, antibiotics, dietary changes, and fecal microbiota transplantation (FMT) are explored, with an emphasis on their effectiveness and safety. The paper also discusses the difficulties in investigating the small intestine microbiota, including methodological constraints and the necessity for tailored treatments. Future research directions are highlighted, with an emphasis on developing technologies and their ability to overcome current limits. This article emphasizes the significance of ongoing research to fully realize the therapeutic potential of the small intestine microbiota in clinical practice.
Abstract (English)
The small intestine microbiota is becoming recognized as performing an important role in human health and illness. This review article investigates the composition and function of the small intestine microbiota, focusing on its role in digestion, nutritional absorption, immunological regulation, and pathogen protection. We investigated the link between microbial dysbiosis and a variety of gastrointestinal, metabolic, immune-mediated, and cognitive conditions. Therapeutic approaches such as probiotics, prebiotics, antibiotics, dietary changes, and fecal microbiota transplantation (FMT) are explored, with an emphasis on their effectiveness and safety. The paper also discusses the difficulties in investigating the small intestine microbiota, including methodological constraints and the necessity for tailored treatments. Future research directions are highlighted, with an emphasis on developing technologies and their ability to overcome current limits. This article emphasizes the significance of ongoing research to fully realize the therapeutic potential of the small intestine microbiota in clinical practice.
Files
IJPCR,Vol16,Issue6,Article9.pdf
Files
(348.8 kB)
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Additional details
Dates
- Accepted
-
2024-05-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue6,Article9.pdf
- Development Status
- Active
References
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