Method Development and Validation for simultaneous Estimation of Aspirin and Ticlopidine HCL in Bulk and Tablet Formulation by using UV Spectrophotometer

A simple,economical,rapid,accurate,precise method for simultaneous estimation was developed and validated. UV Spectrophotometric estimation of Aspirin and Ticlopidine HCL of the bulk and tablet formulation is done in  which distilled water was used as a solvent and methanol is used as a co-solvent. Method used is- Simultaneous Equation Method which was carried out at the wavelength of 275 nm and 214 nm for Aspirin and Ticlopidine HCL respectively. The linearity range was found to be 25-125 µg/ml and 5-25 µg/ml.The recovery studies were performed and percent recoveries were found to be 99.66±0.3932 % and 99.72± 0.2535 % for Aspirin and Ticlopidine HCL. So proposed method was found to be simple,accurate, linear and specifc.