In-Situ Gelling System: A Review
Creators
- 1. Sree Vidyanikethan College of pharmacy, Sree Sainath Nagar, Chandragiri (M), Tiruapti, Andhra Pradesh, India-517102.
Description
Current review on in-situ gelling system explains about gels which are defined as intermediate
state of matter consists of liquid and solid components. Hydrogels are also briefly discussed in
the review that is defined as three dimensional structures which has capacity to retain bulk
amount of water and also biological fluids to swell. In-situ gels are type of hydrogels that are
solution in form and undergo gelation in contact with body fluids or change in pH. Some of the
polymers that are used in in-situ gelling system are guar gum, gellan gum, xanthan gum,
carrageenan, xyloglucan, pectin, chitosan and thiolated chitosan. In this review on in-situ
gelling system, some of the approaches through which in-situ gels can be obtained are also
discussed. It also focuses on the applications of in-situ gels that are the type of novel drug
delivery systems in which these systems can be formulated. Some of the novel drug delivery
systems are oral, nasal, injectable and ophthalmic drug delivery systems.
Abstract (English)
Current review on in-situ gelling system explains about gels which are defined as intermediate
state of matter consists of liquid and solid components. Hydrogels are also briefly discussed in
the review that is defined as three dimensional structures which has capacity to retain bulk
amount of water and also biological fluids to swell. In-situ gels are type of hydrogels that are
solution in form and undergo gelation in contact with body fluids or change in pH. Some of the
polymers that are used in in-situ gelling system are guar gum, gellan gum, xanthan gum,
carrageenan, xyloglucan, pectin, chitosan and thiolated chitosan. In this review on in-situ
gelling system, some of the approaches through which in-situ gels can be obtained are also
discussed. It also focuses on the applications of in-situ gels that are the type of novel drug
delivery systems in which these systems can be formulated. Some of the novel drug delivery
systems are oral, nasal, injectable and ophthalmic drug delivery systems.
Files
IJCPR,Vol5,Issue4,Article2.pdf
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Additional details
Dates
- Accepted
-
2014-11-01