First Trimester Screening for Prediction of Preeclampsia with Maternal Characteristics, Uterine Artery Doppler and Mean Arterial Pressure
Creators
- 1. Ex Junior Resident, Department of Obs & Gynae, MMIMSR, MMDU, Mullana, Ambala, Haryana, India
- 2. Prof & HOD, Department of Obs & Gynae, MMIMSR, MMDU, Mullana, Ambala, Haryana, India
- 3. 3rd Year PG Junior Resident, Department of Obs & Gynae, MMIMSR, MMDU, Mullana, Ambala, Haryana, India
- 4. Associate Professor, Department of Obs & Gynae, MMIMSR, MMDU, Mullana, Ambala, Haryana, India
Description
Aim: First trimester screening for prediction of preeclampsia with maternal characteristics, uterine artery doppler and mean arterial pressure. Materials and Methods: The present study was done in pregnant women attending outpatient Department of Obstetrics and Gynaecology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana. This study was conducted from Jan 2020 – June 2021. Women, giving consent for participation in the study; between 11-13+6 weeks; Spontaneous conception were included in the study. Fetal Congenital abnormalities detected any time during pregnancy. Results: 129 pregnant women were included. Majority of pregnant women included were in the age group of 25-29 years. Out of the total 129 women in our study group, 18(13.95%) developed preeclampsia. Incidence of preeclampsia was highest (33.0%) in the age group of 20-24 years and 30-35 years. 7.0% female developing preeclampsia were aged 25-29 years and above 35 years. 3 (16.6%) Women developed early onset pre-eclampsia whilst the rest 83.4 % i.e. 15 females had late onset pre-eclampsia amongst which 5 gestational hypertension followed by proteinuria and eventually late onset pre-eclampsia. In 45% (5/11) women who had past history of pre-eclampsia/ gestational hypertention developed pre-eclampsia in present pregnancy. 4 out of 6 women (66%) with past history of chronic hypertension developed pre-eclampsia. In our study 3 out of 3 women (100%) who were APS positive had pre-eclampsia in present pregnancy. 72% of the women with preeclampsia had a mean arterial pressure of more than 90mmHg. On bilateral uterine artery Doppler, 39% of women had a raised palatability value. Majority of women (89%) with the presence of a diastolic notch developed pre-eclampsia. Past history of pre-eclampsia, advanced maternal age, gestational, raised pulsatility index, presence of diastolic notch showed association with adverse pregnancy outcome. Conclusion: A detailed history for first trimester (11-13+6 weeks) detection of maternal characteristics, MAP along with uterine artery Doppler (PI, RI and diastolic notch) are helpful in early prediction of preeclampsia. There is a statistically significant correlation of presence of diastolic notch on uterine artery doppler with development of preeclampsia. In a low resource country like India prediction of preeclampsia with maternal characteristics, mean arterial pressure and uterine artery doppler is not only cost effective but a non-invasive modality for prediction of pre-eclampsia so that preventive measures can be implemented well in time to avoid catastrophic maternal and fetal outcomes.
Abstract (English)
Aim: First trimester screening for prediction of preeclampsia with maternal characteristics, uterine artery doppler and mean arterial pressure. Materials and Methods: The present study was done in pregnant women attending outpatient Department of Obstetrics and Gynaecology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana. This study was conducted from Jan 2020 – June 2021. Women, giving consent for participation in the study; between 11-13+6 weeks; Spontaneous conception were included in the study. Fetal Congenital abnormalities detected any time during pregnancy. Results: 129 pregnant women were included. Majority of pregnant women included were in the age group of 25-29 years. Out of the total 129 women in our study group, 18(13.95%) developed preeclampsia. Incidence of preeclampsia was highest (33.0%) in the age group of 20-24 years and 30-35 years. 7.0% female developing preeclampsia were aged 25-29 years and above 35 years. 3 (16.6%) Women developed early onset pre-eclampsia whilst the rest 83.4 % i.e. 15 females had late onset pre-eclampsia amongst which 5 gestational hypertension followed by proteinuria and eventually late onset pre-eclampsia. In 45% (5/11) women who had past history of pre-eclampsia/ gestational hypertention developed pre-eclampsia in present pregnancy. 4 out of 6 women (66%) with past history of chronic hypertension developed pre-eclampsia. In our study 3 out of 3 women (100%) who were APS positive had pre-eclampsia in present pregnancy. 72% of the women with preeclampsia had a mean arterial pressure of more than 90mmHg. On bilateral uterine artery Doppler, 39% of women had a raised palatability value. Majority of women (89%) with the presence of a diastolic notch developed pre-eclampsia. Past history of pre-eclampsia, advanced maternal age, gestational, raised pulsatility index, presence of diastolic notch showed association with adverse pregnancy outcome. Conclusion: A detailed history for first trimester (11-13+6 weeks) detection of maternal characteristics, MAP along with uterine artery Doppler (PI, RI and diastolic notch) are helpful in early prediction of preeclampsia. There is a statistically significant correlation of presence of diastolic notch on uterine artery doppler with development of preeclampsia. In a low resource country like India prediction of preeclampsia with maternal characteristics, mean arterial pressure and uterine artery doppler is not only cost effective but a non-invasive modality for prediction of pre-eclampsia so that preventive measures can be implemented well in time to avoid catastrophic maternal and fetal outcomes.
Files
IJPCR,Vol15,Issue4,Article193.pdf
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Additional details
Dates
- Accepted
-
2023-03-30
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue4,Article193.pdf
- Development Status
- Active
References
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