Published December 30, 2017 | Version v1
Journal article Open

A Review - Herbs in Urinary Tract Infection (UTI)

  • 1. Konkan Gyanpeeth Rahul Dharkar College of Pharmacy, Dahivali, Karjat

Description

Urinary Tract Infection (UTI) affects various part of the urinary tract. When it affects the lower part it is known as a bladder
infection and when it affects the upper part it is known as kidney infection clinically, presence of more than 1 Lakh
organisms per ml of midstream sample of urine (MSU) is an indication of urinary tract infection. A pain and burning feeling
when you urinate, Urethral discharge containing pus or mucus, Frequent and urgent need to urinate especially at night,
Obstructed urinary flow, Lower back pain, Unexplained fever, Cloudy urine with visible blood are the common symptoms
of UTI. Cranberry, blue berry, berberine, bearberry, buchu oil etc are found to be effective in urinary tract infection. The
fimbriae of E.coli produce two types of adhesins such as mannose sensitive and mannose resistant adhesins that attach to
receptors on uroepithelial cells. Proanthocyanidin obtained from cranberry, blueberry etc shows extreme inhibitory
activity against mannose-resistant adhesins. In bearberry the active antimicrobial activity is shown by aglycone
hydroquinone which is released in alkaline urine. Buchu leaf is a diuretic and urinary tract antiseptic Urinary tract antiseptic
activity is may be due to its essential oil. The essential oil consists mainly of the monoterpene diosphenol.

Abstract (English)

Urinary Tract Infection (UTI) affects various part of the urinary tract. When it affects the lower part it is known as a bladder
infection and when it affects the upper part it is known as kidney infection clinically, presence of more than 1 Lakh
organisms per ml of midstream sample of urine (MSU) is an indication of urinary tract infection. A pain and burning feeling
when you urinate, Urethral discharge containing pus or mucus, Frequent and urgent need to urinate especially at night,
Obstructed urinary flow, Lower back pain, Unexplained fever, Cloudy urine with visible blood are the common symptoms
of UTI. Cranberry, blue berry, berberine, bearberry, buchu oil etc are found to be effective in urinary tract infection. The
fimbriae of E.coli produce two types of adhesins such as mannose sensitive and mannose resistant adhesins that attach to
receptors on uroepithelial cells. Proanthocyanidin obtained from cranberry, blueberry etc shows extreme inhibitory
activity against mannose-resistant adhesins. In bearberry the active antimicrobial activity is shown by aglycone
hydroquinone which is released in alkaline urine. Buchu leaf is a diuretic and urinary tract antiseptic Urinary tract antiseptic
activity is may be due to its essential oil. The essential oil consists mainly of the monoterpene diosphenol.

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Dates

Accepted
2017-02-25