Correlation of Serum Anti Tissue Transglutaminase Immunoglobulin-A Levels with Weight, Height and Haemoglobin in Cases of Celiac Disease
Creators
- 1. Assistant Professor, Department of Paediatrics, Chirayu Medical College, Bhopal, MP
- 2. Assistant Professor, Mahaveer Institute of Medical Science and Research, Bhopal, MP
- 3. Senior Resident, Department of Paediatrics, Chirayu Medical College, Bhopal, MP
Description
Objective: Correlation of serum anti tissue transglutaminase immunoglobulin-A levels with weight, height and haemoglobin. Correlation of staging with weight, height and haemoglobin. Abdominal ultrasonography finding in cases of celiac disease. Methods: This was a prospective analytical study conducted in Department of Pediatrics, Umaid Hospital, Dr. S.N. Medical College, Jodhpur in children attending outpatient department and patients admitted in wards. Patients of with age less than 18 years were included in the study. The study was conducted over period of one year from January 2014 to December 2014. Total 52 patients were enrolled in study. Results: The most common finding on abdominal ultrasound was distended bowel loops which were present in fifteen (28.84%) cases on upper gastrointestinal endoscopy villous atrophy was seen in 33 (63.46%) cases. There was no correlation between serum tissue transglutaminase IgA levels and clinical parameters like weight, height, hemoglobin .There was no correlation between serum tissue transglutaminase IgA levels and abdominal ultrasonography finding. Conclusion: There is significant correlation between serum anti tissue transglutaminase immunoglobulin A levels. Endoscopy and biopsy may not be necessary for diagnosis of celiac disease. Whenever levels of serum anti tissue transglutaminase immunoglobulin levels are inconclusive then endoscopy and biopsy is helpful in diagnosis. This will avoid an invasive procedure and lead to a more rapid diagnosis and earlier treatment of celiac disease.
Abstract (English)
Objective: Correlation of serum anti tissue transglutaminase immunoglobulin-A levels with weight, height and haemoglobin. Correlation of staging with weight, height and haemoglobin. Abdominal ultrasonography finding in cases of celiac disease. Methods: This was a prospective analytical study conducted in Department of Pediatrics, Umaid Hospital, Dr. S.N. Medical College, Jodhpur in children attending outpatient department and patients admitted in wards. Patients of with age less than 18 years were included in the study. The study was conducted over period of one year from January 2014 to December 2014. Total 52 patients were enrolled in study. Results: The most common finding on abdominal ultrasound was distended bowel loops which were present in fifteen (28.84%) cases on upper gastrointestinal endoscopy villous atrophy was seen in 33 (63.46%) cases. There was no correlation between serum tissue transglutaminase IgA levels and clinical parameters like weight, height, hemoglobin .There was no correlation between serum tissue transglutaminase IgA levels and abdominal ultrasonography finding. Conclusion: There is significant correlation between serum anti tissue transglutaminase immunoglobulin A levels. Endoscopy and biopsy may not be necessary for diagnosis of celiac disease. Whenever levels of serum anti tissue transglutaminase immunoglobulin levels are inconclusive then endoscopy and biopsy is helpful in diagnosis. This will avoid an invasive procedure and lead to a more rapid diagnosis and earlier treatment of celiac disease.
Files
IJPCR,Vol15,Issue4,Article89.pdf
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Additional details
Dates
- Accepted
-
2023-04-03
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue4,Article89.pdf
- Development Status
- Active
References
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