Study on Clinical Profile of Neonatal Seizures with Special Reference to Biochemical Abnormalities in NICU
- 1. Bhagwan Mahavir Institute of Medical Sciences, Pawapuri
Description
Background: Neonatal seizures are clinically significant because very few are idiopathic. Biochemical disturbances occur frequently in neonatal seizures either as an underlying cause or as associated abnormalities. In their presence it is difficult to control seizures and there is a risk of further brain damage. Methodology: The present study included 110 neonates presenting with seizures admitted to NICU at BMIMS, Pawapuri. Study duration of Two years. Detailed antenatal, natal and postnatal history were taken and examination of baby was done and HIE staged according to modified Sarnat’s staging. Relevant investigations including biochemical parameters were done and etiology of neonatal seizures and their associated biochemical abnormalities were diagnosed. Conclusion: Biochemical abnormalities are common in neonatal seizures. Isolated biochemical abnormalities without other co morbid states were seen in 13 (11.8%) cases. 33 (30%) cases of neonatal seizures with identifiable etiology had associated biochemical abnormalities.
Abstract (English)
Background: Neonatal seizures are clinically significant because very few are idiopathic. Biochemical disturbances occur frequently in neonatal seizures either as an underlying cause or as associated abnormalities. In their presence it is difficult to control seizures and there is a risk of further brain damage. Methodology: The present study included 110 neonates presenting with seizures admitted to NICU at BMIMS, Pawapuri. Study duration of Two years. Detailed antenatal, natal and postnatal history were taken and examination of baby was done and HIE staged according to modified Sarnat’s staging. Relevant investigations including biochemical parameters were done and etiology of neonatal seizures and their associated biochemical abnormalities were diagnosed. Conclusion: Biochemical abnormalities are common in neonatal seizures. Isolated biochemical abnormalities without other co morbid states were seen in 13 (11.8%) cases. 33 (30%) cases of neonatal seizures with identifiable etiology had associated biochemical abnormalities.
Files
IJPCR,Vol15,Issue4,Article5.pdf
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Additional details
Dates
- Accepted
-
2023-03-20
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue4,Article5.pdf
- Development Status
- Active
References
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