Published May 30, 2023 | Version v1
Journal article Open

The Effect of Intravenous Tramadol Administration on Postoperative Pain Relief Post Caesarean Section

  • 1. Associate Professor, Department of Obstetrics and Gynaecology, Kempegowda Institute of Medical Sciences, Bangalore, Karnataka, India
  • 2. Post Graduate, Department of Obstetrics and Gynaecology, Kempegowda Institute of Medical Sciences, Bangalore, Karnataka, India

Description

Abstract
Background: Tramadol administered intravenously has been demonstrated to decrease post
operative pain. In this study, the effect of intravenous tramadol administration on pain relief
after caesarean section has been studied.
Methods: 100 Women following elective/emergency caesarean section were included and
were divided into two groups, 50 in each. Group A received IV 100ml normal saline infusion
over 15-20 minutes. Group B received 50 mg Tramadol intravenous infusion (1ml ampule in
100ml NS over 15-20 minutes). Post caesarean pain was assessed by visual analogue scale
and by examining the patient at start of recruitment and 15mins, 1hour, 2hours, 3hours and
4hours post section. Drug was administered 2 hours post section or 4 hours post spinal
(considering average effect of spinal anaesthesia as 2 hours).
Results: Mean pain intensity assessed on VAS was significantly better for tramadol group
compared to placebo group at all the time points. Maximum fall in pain intensity score was
also significantly superior in the tramadol group as compared to the placebo group. No
patients required rescue medication in Tramadol group.
Conclusion: Tramadol has more pronounced analgesic effect. Thus, Tramadol can be
considered as an effective analgesic in treatment of post operative pain in post caesarean
patients

Abstract (English)

Abstract
Background: Tramadol administered intravenously has been demonstrated to decrease post
operative pain. In this study, the effect of intravenous tramadol administration on pain relief
after caesarean section has been studied.
Methods: 100 Women following elective/emergency caesarean section were included and
were divided into two groups, 50 in each. Group A received IV 100ml normal saline infusion
over 15-20 minutes. Group B received 50 mg Tramadol intravenous infusion (1ml ampule in
100ml NS over 15-20 minutes). Post caesarean pain was assessed by visual analogue scale
and by examining the patient at start of recruitment and 15mins, 1hour, 2hours, 3hours and
4hours post section. Drug was administered 2 hours post section or 4 hours post spinal
(considering average effect of spinal anaesthesia as 2 hours).
Results: Mean pain intensity assessed on VAS was significantly better for tramadol group
compared to placebo group at all the time points. Maximum fall in pain intensity score was
also significantly superior in the tramadol group as compared to the placebo group. No
patients required rescue medication in Tramadol group.
Conclusion: Tramadol has more pronounced analgesic effect. Thus, Tramadol can be
considered as an effective analgesic in treatment of post operative pain in post caesarean
patients

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Dates

Accepted
2023-04-30