Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad
Authors/Creators
- 1. Associate Professor, Department of Pathology, Mamata Academy of Medical Sciences, Hyderabad
- 2. Assistant Professor, Department of Pathology, Mamata Academy of Medical Sciences, Hyderabad
- 3. Resident, Department of Pathology, Bidar Institute of Medical Sciences
- 4. Associate Professor, Department of Dermatology, Venerology & Leprosy, Mamata Academy of Medical Sciences, Hyderabad
Description
Background: Papulosquamous disorders, characterised by scaly papules and plaques are one of the most common skin dermatoses seen by dermatologists. Some of the examples of papulosquamous skin disorders include lichen planus, psoriasis, pityriasis rosea, pityriasis rubra pilaris, parapsorias etc. Due to clinical and morphological overlap, it is sometimes difficult to make a straight forward clinical diagnosis without histological confirmation. Some of the histopathological features are specific and characteristic for each entity. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis. Aims and Objectives: The present study aims to analyse various histopathological patterns of papulosquamous lesions of the skin based on the tissue reaction pattern and assess the concordance of provisional clinical diagnosis and histopathological diagnosis. Materials And Methods: This is a hospital based retrospective study of 2 year duration from 2021-2022, at Department of pathology. Descriptive data on clinical history and histopathological examination of all the cases of papulosquamous lesions of skin was collected and results were drawn on various parameters using statistical analysis tools. Results: Out of total 90 cases of clinically suspicious papulosquamous disorders, only 74 cases confirmed as various papulosquamous disorders histopathologically with a positive correlation of 82.2 % and negative correlation of 17.7%. Majority (23 cases) were in the age group of 31 to 40 years. There was slight male preponderance with male: female ratio being 1.14:1.The commonest diagnosis was Lichen planus and its variants (23 cases), followed by Psoriasis and its variants (19 cases), eczema (17 cases),pityriasis rosea (5 cases), Lichen nitidus (3cases), Lichenoid dermatitis (3 cases), Parapsoriasis (2 cases), 1 case each of pityriasis rubra pilaris and chronic cutaneous lupus. Conclusion: The present study is designed to know the correlation between the clinical patterns of various papulosquamous disorders and their histopathological diagnosis .There are many studies done on clinical correlation with histopathological diagnosis but still the positive correlation is not reaching up to 100%, some studies have negative correlation of around 40%. Therefore, more studies are required in this field to appropriately diagnose and manage the papulosquamous disorders in order to reduce the disease burden and as a key to better patient care.
Abstract (English)
Background: Papulosquamous disorders, characterised by scaly papules and plaques are one of the most common skin dermatoses seen by dermatologists. Some of the examples of papulosquamous skin disorders include lichen planus, psoriasis, pityriasis rosea, pityriasis rubra pilaris, parapsorias etc. Due to clinical and morphological overlap, it is sometimes difficult to make a straight forward clinical diagnosis without histological confirmation. Some of the histopathological features are specific and characteristic for each entity. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis. Aims and Objectives: The present study aims to analyse various histopathological patterns of papulosquamous lesions of the skin based on the tissue reaction pattern and assess the concordance of provisional clinical diagnosis and histopathological diagnosis. Materials And Methods: This is a hospital based retrospective study of 2 year duration from 2021-2022, at Department of pathology. Descriptive data on clinical history and histopathological examination of all the cases of papulosquamous lesions of skin was collected and results were drawn on various parameters using statistical analysis tools. Results: Out of total 90 cases of clinically suspicious papulosquamous disorders, only 74 cases confirmed as various papulosquamous disorders histopathologically with a positive correlation of 82.2 % and negative correlation of 17.7%. Majority (23 cases) were in the age group of 31 to 40 years. There was slight male preponderance with male: female ratio being 1.14:1.The commonest diagnosis was Lichen planus and its variants (23 cases), followed by Psoriasis and its variants (19 cases), eczema (17 cases),pityriasis rosea (5 cases), Lichen nitidus (3cases), Lichenoid dermatitis (3 cases), Parapsoriasis (2 cases), 1 case each of pityriasis rubra pilaris and chronic cutaneous lupus. Conclusion: The present study is designed to know the correlation between the clinical patterns of various papulosquamous disorders and their histopathological diagnosis .There are many studies done on clinical correlation with histopathological diagnosis but still the positive correlation is not reaching up to 100%, some studies have negative correlation of around 40%. Therefore, more studies are required in this field to appropriately diagnose and manage the papulosquamous disorders in order to reduce the disease burden and as a key to better patient care.
Files
IJPCR,Vol15,Issue5,Article273.pdf
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(5.6 MB)
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Additional details
Dates
- Accepted
-
2023-05-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue5,Article273.pdf
- Development Status
- Active
References
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