One Year Cross-Sectional Study of Pulmonary Function Abnormalities and Type 2 Diabetes Mellitus
Authors/Creators
- 1. Assistant Professor, Department of Medicine, Darbhanga Medical College and Hospital, Laheriasarai, Bihar
- 2. Associate Professor, Department of Medicine, Darbhanga Medical College and Hospital, Laheriasarai, Bihar
Description
Background: One of the most prevalent chronic disease worldwide, diabetes mellitus is on the rise as people’s lifestyles change, resulting in decreased physical activity and rising obesity rates. India will have the highest rate of diabetes worldwide in 2025, according to a WHO survey. Since type II diabetes makes up 90 to 95% of all cases of diabetes and its prevalence is rising. In its early stages, it is frequently asymptomatic and might go years without being identified. Despite lungs facing extensive microvascular networks, investigations on the relationship between diabetes and poor pulmonary function are conflicting. Methods: An equal number of individuals who were not diabetic and 90 diabetic patients participated in a cross-sectional study. Both groups rates of pulmonary function test (PFT) abnormalities were estimated. Taking into account additional risk variables for deteriorated lung function, logistic regression was utilised to identify independent relationship between diabetes and its consequences. Results: 52 (58%) of non-diabetic patients and 71 (79%) (95% CI= 69.0 – 86.0) of 90 diabetic patients had abnormal PFT (p=0.02). While 29 (32%) of the diabetic people had an obstructive pattern (95% CI= 22.9-43.0), 42 (47%) of them had a restrictive pattern (95% CI= 36.0-57.4). In a multivariate study, only age, female sex, and BMI showed a significant correlation with abnormal PFT, but the presence of diabetes, age, female sex, glycosylated haemoglobin, and body mass index (BMI) did not. Conclusion: The presence of diabetes and impaired lung function did not independently correlate. Ageing, having a higher BMI, and being a woman all stood alone as risk factors for pulmonary dysfunction.
Abstract (English)
Background: One of the most prevalent chronic disease worldwide, diabetes mellitus is on the rise as people’s lifestyles change, resulting in decreased physical activity and rising obesity rates. India will have the highest rate of diabetes worldwide in 2025, according to a WHO survey. Since type II diabetes makes up 90 to 95% of all cases of diabetes and its prevalence is rising. In its early stages, it is frequently asymptomatic and might go years without being identified. Despite lungs facing extensive microvascular networks, investigations on the relationship between diabetes and poor pulmonary function are conflicting. Methods: An equal number of individuals who were not diabetic and 90 diabetic patients participated in a cross-sectional study. Both groups rates of pulmonary function test (PFT) abnormalities were estimated. Taking into account additional risk variables for deteriorated lung function, logistic regression was utilised to identify independent relationship between diabetes and its consequences. Results: 52 (58%) of non-diabetic patients and 71 (79%) (95% CI= 69.0 – 86.0) of 90 diabetic patients had abnormal PFT (p=0.02). While 29 (32%) of the diabetic people had an obstructive pattern (95% CI= 22.9-43.0), 42 (47%) of them had a restrictive pattern (95% CI= 36.0-57.4). In a multivariate study, only age, female sex, and BMI showed a significant correlation with abnormal PFT, but the presence of diabetes, age, female sex, glycosylated haemoglobin, and body mass index (BMI) did not. Conclusion: The presence of diabetes and impaired lung function did not independently correlate. Ageing, having a higher BMI, and being a woman all stood alone as risk factors for pulmonary dysfunction.
Files
IJPCR,Vol15,Issue5,Article267.pdf
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Additional details
Dates
- Accepted
-
2023-04-30
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue5,Article267.pdf
- Development Status
- Active
References
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